Assessment of Quality Of Life Outcomes in the Treatment of Advanced Colorectal Malignancies

Lifting symptom burden—how far off the ground are we?

“…Randomized controlled trials support the symptom benefits to chemotherapy. Despite the relatively small survival benefits in lung and colorectal cancer, QOL is better with palliative chemotherapy vs. supportive care [36,41]. Therefore, symptom treatment benefits and disease-related burden should be constantly required as outcomes to palliative anti-tumor trials.…”

Operative colonoscopy in cancer patients

“…Patients with unresectable or recurrent CRC may have symptoms of obstruction, pain, and haemorrhage, which are indispensable to receive palliative treatment in order to improve the quality of life and, eventually, to increase the duration of survival. Surgical treatments are associated with significant postoperative morbidity (20%-30%) and mortality (5%-10%) for advanced CRC patients (22). During the last decades, the endoscopic technologies have become well-established non-surgical palliative procedure to relieve the disease-related symptoms.…”