Abstract. Purpose of the study. The article discusses an algorithm for using the categories of the International Classification of Functioning, Disability and Health (ICF) for comparative assessment of the effectiveness of various medical rehabilitation programs for patients with polypoid rhinosinusitis. It is shown that the use of the ICF makes it possible to implement a systematic approach to assessing the efficacy of rehabilitation measures, taking into account the biopsychosocial model for assessing health (illness) and the category of functioning, which serves as the basis for the integration process of rehabilitation. The results of comparative monitoring of the formed categorical profile of a patient with polypoid rhinosinusitis convincingly proved the advantages of complex medical rehabilitation of patients with nasal polyposis, based on biological therapy with dupilumab in combination with a course application of an alternating magnetic field and low-intensity laser radiation.