Assessment of relation between aortic elastic properties and the complexity of coronary artery disease

Karakurt, Ahmet; Yıldız, Cennet; Yıldız, Atilla; Başbuğ, Hamit Serdar

doi:10.1080/ac.71.3.3152086

Cited by 7 publications

(8 citation statements)

References 26 publications

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“…Similar to our study Karakurt et al [ 41 ] found that ASI, AS, and elasticity were related to the severity of coronary artery disease; however, their study included three hundred sixty-seven patients of both sex. In the same context, El-Naggar et al [ 42 ] concluded in their study that simple M-mode-derived aortic elasticity indices might predict patients with more severe and complex CAD.…”

Section: Discussionsupporting

confidence: 87%

Relation between aortic elasticity parameters and SYNTAX score in postmenopausal diabetic women

Naseem

Alaarag

2023

Egypt Heart J

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Background Postmenopausal women are at increased risk of coronary artery disease (CAD). Diabetes Mellitus is a major risk factor for CAD. The stiffening of the aorta is associated with increased cardiovascular morbidity and mortality. We aimed to investigate the relation of aortic elasticity parameters to CAD severity assessed by SYNTAX score (SS) in diabetic postmenopausal women. The study prospectively included 200 consecutive diabetic postmenopausal women with CAD who underwent elective coronary angiography. Patients were classified into 3 groups based on SS, low-SS ≤ 22, intermediate-SS ≥ 23– ≤ 32, and high-SS ≥ 33. Echocardiographic aortic elasticity parameters, including aortic stiffness index (ASI), aortic strain (AS) (%) and aortic distensibility (AD) were obtained in all patients. Results Patients in the high SS group were older age and had a higher aortic stiffness. After adjusting different co-variates AD, AS, and ASI could be used as independent predictors of high SS with the following P-values (0.019, 0.016 and 0.010) and cut-off values (2.5, 3.6 and 2.9), respectively. Conclusions In diabetic postmenopausal women, the simple echocardiography-derived aortic elasticity parameters might predict the severity and complexity of angiographic coronary lesions assessed by the SS.

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Section: Discussionsupporting

confidence: 87%

Relation between aortic elasticity parameters and SYNTAX score in postmenopausal diabetic women

Naseem

Alaarag

2023

Egypt Heart J

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“…These results were concordant with Karakurt et al . [ 10 ] Ghaderi et al ., as well, showed that aortic strain and AD had significant inverse correlation with presence and severity of CAD assessed with SS. [ 19 ]…”

Section: Discussionmentioning

confidence: 99%

“…Some studies reported the association between AD and stiffness indices and severity of coronary atherosclerosis assessed by either the Gensini score[ 1 ] or the SYNTAX Score (SS),[ 10 ] however with no clear cutoff points for such indices. The SS is a lesion-based angiographic scoring system originally devised to grade the complexity of CAD.…”

Section: Introductionmentioning

confidence: 99%

Aortic Elasticity Indices as Predictors of Coronary Artery Disease Severity Assessed by SYNTAX Score

El-Naggar

Anwar

Helmy

et al. 2021

Journal of Cardiovascular Echography

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Background: Aortic elastic properties have been related to coronary artery disease (CAD) morbidity and mortality. We aimed to assess the relation of aortic elasticity indices to the severity and complexity of CAD assessed using the SYNTAX Score (SS), evaluating which of these indices have better predictivity for CAD severity. Materials and Methods: We prospectively enrolled 150 individuals who underwent elective coronary angiography for suspected CAD, out of them 29 (19.3%) had normal or nonsignificant angiographic findings (Group I), whereas 121 (80.7%) had significant CAD (Group II) for whom the SS was calculated. Echo-derived aortic elasticity indices were performed for all patients. Results: Logistic regression analyses showed that each of aortic distensibility, stiffness index, elastic modulus, aortic strain, and aortic peak early diastolic velocity were predictors for significant CAD and further for more complex CAD as indicated by intermediate-high SS. Receiver operator characteristic curves-derived cutoff points were performed for each of the aortic elasticity indices. Along with diabetes, decreased aortic strain ≤10.2% was the only independent predictor of intermediate-high SS (odds ratio = 4.31, 95% confidence interval = 1.38–13.50, P = 0.01). Conclusion: Simple M-mode derived aortic elasticity indices, particularly aortic strain ≤10.2%, might predict patients with more severe and complex CAD.

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“…It has been shown that there is a relationship between the presence of CAD and deterioration in the elastic parameters of the aorta. 18 A relationship has been found between the presence and severity of CAD and the aortic distensibility and strain. 19 Aortic pulse pressure and pulsatility index have been shown to be increased in patients with CSF.…”

Section: Discussionmentioning

confidence: 99%

The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties

Akkaya

Güntürk

2020

JRSM Cardiovascular Disease

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Introduction In this study, we aimed to investigate the relationship between coronary slow flow (CSF) and carotid-femoral pulse wave velocity (CFPWV). Methods 78 (27 women, mean age 43.95 ± 7.28) patients with CSF, and 70 (22 women, mean age 44.34 ± 7.08) healthy individuals were included in the study. Arterial stiffness measurement was performed to both groups via CFPWV, which is considered the gold standard. Aortic elastic properties (ASI-β and aortic distensibility) were evaluated in both groups. Results The CSF group had significantly higher CFPWV and aortic distensibility values and significantly lower ASI-β values compared to the control group. There was a positive correlation between TIMI frame count (TFC) obtained in all coronary arteries and CFPWV and aortic distensibility, and a negative correlation between TFC and ASI-β. It was determined that CFPWV predicted CSF with 97% specificity and 98% sensitivity at a 7.68 cut-off value (ROC area = 994, p < 0.001). ASI-β was determined to predict CSF with 64% specificity and 47% sensitivity at a 2.98 cut-off value (ROC area = 047, p < 0.001). Aortic distensibility was determined to predict CSF with 76% specificity and 79% sensitivity at a 3.94 cut-off value (ROC area = 706, p < 0.001). Conclusion Arterial stiffness increases in CSF patients, suggesting that CSF is a systemic pathology rather than a local disease and that a systemic cause such as atherosclerosis plays a role in etiology.

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Assessment of relation between aortic elastic properties and the complexity of coronary artery disease

Cited by 7 publications

References 26 publications

Relation between aortic elasticity parameters and SYNTAX score in postmenopausal diabetic women

Relation between aortic elasticity parameters and SYNTAX score in postmenopausal diabetic women

Aortic Elasticity Indices as Predictors of Coronary Artery Disease Severity Assessed by SYNTAX Score

The relationship between coronary slow flow phenomenon and carotid femoral pulse wave velocity and aortic elastic properties

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