Assessment of renal artery stenosis by phase-contrast magnetic resonance angiography

Richter, Christiane; Krestin, Gabriël P.; Eichenberger, A C; Schöpke, W; Fuchs, W. A.

doi:10.1007/bf00169596

Cited by 12 publications

(9 citation statements)

References 18 publications

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“…Flow measurements were possible in normal volunteers but proved difficult in stenotic vessels, where flow could only be quantified in a few patients with slight or moderate stenosis (9).…”

mentioning

confidence: 99%

MR Velocity Mapping Measurement of Renal Artery Blood Flow in Patients with Impaired Kidney Function

et al. 1996

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Renal blood flow (RBF) was measured in 9 patients with chronic impaired kidney function using MR velocity mapping and compared to PAH clearance and 99mTc-DTPA scintigraphy. An image plane suitable for flow measurement perpendicular to the renal arteries was chosen from 2-dimensional MR angiography. MR velocity mapping was performed in both renal arteries using an ECG-triggered gradient echo pulse sequence previously validated in normal volunteers. Effective renal plasma flow was calculated from the clearance rate of PAH during constant infusion and the split of renal function was evaluated by 99mTc-DTPA scintigraphy. A reduction of RBF was found, and there was a significant correlation between PAH clearance multiplied by 1/(1-hematocrit) and RBF determined by MR velocity mapping. Furthermore, a significant correlation between the distribution of renal function and the percent distribution of RBF was found.

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“…Flow measurements were possible in normal volunteers but proved difficult in stenotic vessels, where flow could only be quantified in a few patients with slight or moderate stenosis (9).…”

mentioning

confidence: 99%

MR Velocity Mapping Measurement of Renal Artery Blood Flow in Patients with Impaired Kidney Function

et al. 1996

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“…Renal bloodflow measurements in healthy volunteers have shown a good agreement with paraaminohippuric acid clearance measurements (60,61,88). In patients with renal artery stenosis, the renal blood flow was significantly reduced and the systolic peak was displaced in the cardiac cycle in comparison to healthy volunteers (80). Recently, it was shown that 2-D PC breath-hold provided a more reliable renal blood flow measurement than cine PC (3).…”

Section: Clinical Resultsmentioning

confidence: 81%

MR Angiography of Abdominal and Peripheral Arteries

et al. 1996

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This review article deals with MR angiography (MRA) of abdominal and peripheral arteries. Pulsatile flow, respiratory motion and peristalsis impose difficulties in imaging the vascular structures in the abdomen and the lower extremities. Development of new techniques, such as segmentation of the data acquisition, using specific acquisition windows in relation to a cardiac trigger, magnetization preparation of the tissue and phase-encoding re-ordering or sorting, have reduced the artifacts associated with abdominal and peripheral MRA. Clinical MR investigations of the arteries branching from the abdominal aorta such as the renal and mesenteric arteries and arteries in the lower extremities have revealed that severe stenoses or occlusions can be diagnosed accurately while the grading of less severe stenosis is more difficult. The phase-contrast method has been used to quantify blood flow and study the hemodynamics in abdominal and peripheral vessels. Quantitative flow information can be used to diagnose vascular disease and provides important physiological information. More prospective clinical studies, in which recently developed MRA techniques are compared with conventional angiography, are necessary before conclusive decisions can be made as to whether MRA may replace these methods.

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“…MR angiography has now moved from flow‐enhanced (time‐of‐flight or phase‐contrast) sequences to T1‐weighted contrast‐enhanced acquisitions. With time‐of‐flight or phase‐contrast techniques [47–56], MR angiography shows the proximal portion of the renal arteries. Several improvements, e.g.…”

Section: Mr Angiographymentioning

confidence: 99%