Assessment of retinal and optic disc vascular perfusion density in retinitis pigmentosa patients by optical coherence tomography angiography

Abstract

BaCKground:The aim of the study was to evaluate the vascular flow density measured by optical coherence tomography angiography in patients with retinitis pigmentosa and to compare it with normal subjects. MateriaL and Methods: This was a cross-sectional case control study employing 16 eyes of eight patients with retinitis pigmentosa and 16 eyes of eight healthy subjects. Optical coherence tomography angiography was performed in all subjects. The macula was imaged with a 3 × 3 mm scan, whereas for the optic nerve head, a 4.5 × 4.5 mm scan was taken. Macular and optic disc vascular flow perfusion densities were measured. In addition, the FAZ area was calculated. All data were compared in the two groups. resuLts: The vascular flow perfusion density in the macular and in the optic nerve head was significantly lower in the retinitis pigmentosa group when compared with the control group. On the other hand, the foveal avascular zones area was not significantly different from controls. ConCLusion: Patients with retinitis pigmentosa show a decreased macular and optic nerve head perfusion density compared with healthy subjects

Vascular density of optic nerve head in diabetic retinopathy using optical coherence tomography angiography

“…Another study showed that mean RNFL thickness and W-RPC VD were significantly lower in the non-arteritic anterior ischemic optic neuropathy (NAION) group compared to normal group [ 35 ]. Patients with retinitis pigmentosa showed a decreased ONH VD compared with healthy subjects [ 36 ]. In the present study in all segments VD measurements are significantly less in DM than normal control.…”