Assessment of right ventricular systolic function in heart transplant patients: Correlation between echocardiography and cardiac magnetic resonance imaging. Investigation of the accuracy and reliability of echocardiography

Şimşek, Evrim; Nalbantgil, Sanem; Ceylan, Naim; Kılıç, Salih; Kemal, Hatice; Engin, Çağatay; Yağdı, Tahir; Özbaran, Mustafa

doi:10.1111/echo.13650

Cited by 17 publications

(11 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Impairment of RV longitudinal systolic function was also reported by Simsek et al in 43 heart transplant patients. However, in this study RVEF quantified by CMR was preserved, which is consistent with the results of our study. The physiopathology of longitudinal RV systolic function alterations in post–heart transplantation is unclear but in the normal right ventricle, the majority of systolic functions are fulfilled by longitudinal contractions …”

Section: Discussionsupporting

confidence: 93%

Impact of right ventricular systolic function after heart transplantation on exercise capacity

et al. 2020

View full text Add to dashboard Cite

Background: Right ventricular (RV) systolic parameters are difficult to assess in heart transplant recipients (HTRs) compared to healthy people because of discordant data, and their impact on exercise capacity remains undefined. We sought to retrospectively assess the impact of RV systolic function on exercise capacity after heart transplantation. Methods:We analyzed data from 61 HTRs who underwent transthoracic echocardiography (TTE), cardiac magnetic resonance imaging (CMR), and exercise capacity assessment by 6-minute walking test (6MWT) and cardiopulmonary exercise testing (CPET) at 1-and 2-year follow-ups. Results: Transthoracic echocardiography RV longitudinal systolic function includingtricuspid annular plan systolic excursion (TAPSE), peak systolic S′ wave tricuspid annular velocity (PSVtdi) and RV free wall longitudinal strain was decreased at 1 year (respectively, 15 ± 3 mm, 10 ± 3 cm/s, and −19 ± 5%) and at 2 years (respectively, 15 ± 3 mm, 10 ± 2 cm/s, and −20 ± 5%) with no significant difference between both evaluations; meanwhile, RV ejection fraction (RVEF) measured by CMR was preserved. Mean percentage of predicted peak oxygen consumption was altered, but improved between the first and second year (55 ± 18 vs 60 ± 18%, P = .038). PSVtdi was weakly correlated with 6MWT distance (r = .426, P = .017) and RVEF with the predicted distance at 6MWT (r = .410, P = .027) at the 1-year follow-up. Conclusions: Despite decreasing values, RV longitudinal systolic function has a weak impact on exercise capacity of HTRs. PSVtdi and RVEF are the most pertinent parameters to assess the impact of RV systolic function on exercise capacity after heart transplantation. These results should lead to redefine normal RV systolic function thresholds for HTRs. K E Y W O R D S cardiopulmonary exercise testing, echocardiography, functional capacity, heart transplantation, right ventricle | 707 VERSET ET al.

show abstract

Section: Discussionsupporting

confidence: 93%

Impact of right ventricular systolic function after heart transplantation on exercise capacity

et al. 2020

View full text Add to dashboard Cite

show abstract

“…In the patients in whom the RVFAC was measured in the second evaluation (transplanted patients between 2018 and 2019), the immediate POP values showed RV dysfunction according to the cutoff point defined by the ASE (< 35%) 5 . However, these values showed an improvement from the 3 rd month, with levels close to those established in the literature, as normal, for patients with HTx (40-48%) 12,13 . These results showed the same behavior as other qualitative and quantitative parameters found in the medical records (Fig.…”

supporting

confidence: 87%

“…RV quantitative values obtained by 2D ETT compared with cMRI in patients undergoing HTx showed FAC as the value with the best correlation (r = 0.747, p < 0.001). FAC value ≤ 48.5% has a sensitivity and specificity of 90.5% to predict a reduce RV ejection fraction (< 50%) estimated by cMRI (AUC: 0.96; 95% CI, 0.908-1.013) 12 . This RVFAC cutoff point is higher than the previously of 35%, described as normal in the ASE guidelines 5 .…”

mentioning

confidence: 98%

El ventrículo derecho de los corazones trasplantados a 2,640 metros sobre el nivel del mar. Una experiencia latinoamericana

Vasquez-Rodriguez

Medina-Mur

Giraldo

et al. 2021

ACM

View full text Add to dashboard Cite

show abstract

“…FAC is known to be well correlated with RVEF in a recent meta-analysis of cardiology studies [6]. In a recent study comparing MRI-based RVEF to echocardiographic indices in non-critically ill patients, FAC appeared to correlate with RVEF better than TAPSE [7]. FAC has the theoretical advantage to be a global index of RV function, incorporating both longitudinal and free-wall contractility [9].…”

Section: Discussionmentioning

confidence: 99%

Comparison of echocardiographic indices of right ventricular systolic function and ejection fraction obtained with continuous thermodilution in critically ill patients

et al. 2019

View full text Add to dashboard Cite

Background Though echocardiographic evaluation assesses the right ventricular systolic function, which of the existing parameters best reflects the right ventricular ejection fraction (RVEF) in the critically ill patients is still uncertain. We aimed to determine the relationship between echocardiographic indices of right ventricular systolic function and RVEF. Methods Prospective observational study was conducted in a mixed Surgical Intensive Care Unit (Hôpital Lariboisière, Paris, France) from November 2017 to November 2018. All critically ill patients monitored with a pulmonary artery catheter were assessed. We collected echocardiographic indices of right ventricular function (tricuspid annular plane systolic excursion, TAPSE; peak systolic velocity of pulsed tissue Doppler at lateral tricuspid annulus, S′; fractional area change, FAC; right ventricular index of myocardial performance, RIMP; isovolumic acceleration, IVA; end-diastolic diameter ratio, EDDr) and compared them with the RVEF obtained from continuous volumetric pulmonary artery catheter. Results Twenty-five patients were analyzed. Admission diagnosis was acute heart failure in 11 patients and septic shock in 14 patients. Median age was 70 years [57–80], norepinephrine median dose was 0.29 μg/kg/min [0.14–0.50], median Sequential Organ Failure Assessment score was 12 [10–14], and mortality at day 28 was 56%. When compared to RVEF, TAPSE had the highest correlation coefficient (rho = 0.78, 95% CI 0.52 to 0.89, p < 0.001). S′ was also correlated to RVEF (rho = 0.64, 95% CI 0.60 to 0.80, p = 0.001) whereas FAC, RIMP, IVA, and EDDr did not. TAPSE lower than 16 mm, S′ lower than 11 cm/s, and EDDr higher than 1 were always associated with a reduced RVEF. Conclusions We found that amongst indices of right ventricular systolic function, TAPSE and S′ were well correlated with thermodilution-derived RVEF in critically ill patients.

show abstract

Assessment of right ventricular systolic function in heart transplant patients: Correlation between echocardiography and cardiac magnetic resonance imaging. Investigation of the accuracy and reliability of echocardiography

Cited by 17 publications

References 18 publications

Impact of right ventricular systolic function after heart transplantation on exercise capacity

Impact of right ventricular systolic function after heart transplantation on exercise capacity

El ventrículo derecho de los corazones trasplantados a 2,640 metros sobre el nivel del mar. Una experiencia latinoamericana

Comparison of echocardiographic indices of right ventricular systolic function and ejection fraction obtained with continuous thermodilution in critically ill patients

Contact Info

Product

Resources

About