Methodological recommendations summarize and systematize the results of scientific and expert activities of the Faculty of Soil Science of Moscow State University on the ecological assessment of pesticides registering in the Russian Federation. This guideline describes the registration requirements for pesticides, laboratory and field methods of their testing, tools for predicting concentrations of pesticides in soil, ground and surface waters, and atmospheric air. Procedures for assessing the hazard and risk of pesticides for the environment and non-target species of wildlife organisms are proposed.