In the present study coagulation process was used as pretreatment for the RO membrane with turbid raw water collected from Bisalpur Dam, Rajasthan, India. To optimize coagulation performance, three kinds of coagulants, namely, Alum (commercially available), synthesized inorganic polymeric coagulant-medium basicity (IPC-M), and inorganic polymeric coagulant-ultra high basicity (IPC-UH) were examined for turbidity removal with varying operating parameters. It was observed that in the optimum pH range of 6–7, the IPC-UH resulted as the best performing coagulant with 0.99 mg/L equivalent Al2O3 dose revealing 2 NTU residual turbidity and residual aluminium of 0.001 mg/L. Moreover, Langelier saturation index and Ryznar stability index values were evaluated at optimum conditions of all the three coagulants proclaiming negligible scaling potential. Furthermore, the coagulant-treated water (100 L) was fed to the RO membrane, and the performance was noted in terms of flux, pressure, and TDS. It was observed that IPC-UH has the lowest reduction in permeate flux of 0.78 L/min/m2 compared to commercially available coagulant alum (0.90 L/min/m2). Also, the increased feed pressure was observed for all the coagulants treated water with the lowest value of 2.3 kg/cm2 for IPC-UH, which was 2.5 kg/cm2 for Alum (commercially available coagulant). Henceforth, integration of coagulation before the RO system resulted in effective pretreatment of turbid water with very minute scaling.