Assessment of T2 Relaxation Times for Normal Canine Knee Articular Cartilage by T2 Mapping Using 1.5-T Magnetic Resonance Imaging

Matsui, Asami; Shimizu, Miki; Beale, Brian S.; Takahashi, Fumitaka; Yamaguchi, Sinya

doi:10.3415/vcot-17-01-0014

Cited by 4 publications

(4 citation statements)

References 35 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Currently, apart from the manufacturer's instructions, there are no guidelines regarding the positioning of the dog for knee imaging. In other articles, dogs were placed in the dorsal (2,5,12,23,24,32,40,43,44) lateral (4,11,36,37) or bridge position (15).…”

Section: Discussionmentioning

confidence: 99%

Assessment of the usefulness of image reconstruction in the oblique and double-oblique sagittal planes for magnetic resonance imaging of the canine cranial cruciate ligament

Przeworski

Adamiak²,

Nowicki³

et al. 2021

Journal of Veterinary Research

View full text Add to dashboard Cite

Introduction The aim of the study was to determine the quality and significance of the magnetic resonance image of the canine knee after reconstruction in the oblique and double-oblique sagittal plane. This reconstruction and 3D images are rarely used in common protocols due to the longer study time they require. The study aimed to demonstrate significance for such diagnostic images in specific sequences in order to stimulate consideration of their more frequent use in diagnosis of diseases of the cruciate ligament in dogs. Material and Methods All tests were carried out using an open magnetic resonance tomography scanner with magnetic field induction. The images obtained from the 30 canine patients examined were reconstructed and evaluated by independent appraisers. Statistical analysis was performed. Results The study showed that MRI of the stifle joint using 3D sequences provides higher quality images of the cranial cruciate ligament in dogs. The results of the statistical analysis showed that multi-faceted reconstruction allows the secondary determination of the oblique imaging planes and obtains images of adequate quality. Conclusion It can be concluded that multi-faceted reconstruction facilitates the secondary determination of oblique imaging planes. This reconstruction additionally makes images available of better quality compared to the 2D sequence.

show abstract

Section: Discussionmentioning

confidence: 99%

Assessment of the usefulness of image reconstruction in the oblique and double-oblique sagittal planes for magnetic resonance imaging of the canine cranial cruciate ligament

Przeworski

Adamiak²,

Nowicki³

et al. 2021

Journal of Veterinary Research

View full text Add to dashboard Cite

show abstract

“…In total there have been four previous studies in which T2 relaxation times have been quantified in dogs. Two of these studies evaluated normal dog knees, one study used normal canine elbows, and there was the aforementioned study that evaluated both normal dog knees and knees in which a subchondral bone defect had been created . The mean T2 value for two of these studies were 52–70 ms while the mean T2 values for the other two studies were 28–48 ms .…”

Section: Discussionmentioning

confidence: 99%

“…Two of these studies evaluated normal dog knees, one study used normal canine elbows, and there was the aforementioned study that evaluated both normal dog knees and knees in which a subchondral bone defect had been created . The mean T2 value for two of these studies were 52–70 ms while the mean T2 values for the other two studies were 28–48 ms . The range in meant T2 relaxation times in the current study were 52–66 ms (Table ) and thus fall within the range of T2 values previously reported in dogs.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

T1ρ, T2 mapping, and EPIC‐µCT Imaging in a Canine Model of Knee Osteochondral Injury

Franklin

Stoker

Lin

et al. 2019

Journal Orthopaedic Research

View full text Add to dashboard Cite

The dog is the most commonly used large animal model for the study of osteoarthritis. Optimizing methods for assessing cartilage health would prove useful in reducing the number of dogs needed for a valid study of osteoarthritis and cartilage repair. Twelve beagles had critical-sized osteochondral defects created in the medial femoral condyle of both knees. Eight dogs had T1ρ and T2 magnetic resonance imaging (MRI) performed approximately 6 months after defect creation. Following MRI evaluations, all 12 dogs were humanely euthanatized and cartilage samples were obtained from the medial and lateral femoral condyles, medial and lateral tibial plateaus, trochlear groove, and patella for proteoglycan and collagen quantification. Equilibrium partitioning of an ionic contrast (EPIC)-µCT was then performed followed by the histologic assessment of the knees. Correlations between T1ρ, T2, EPIC-µCT and proteoglycan, collagen, and histology scores were assessed using a multivariate analysis accounting for correlations from samples within the same knee and in the same dog. Pearson's correlation coefficients were calculated to assess the strength of significant relationships. Correlations between µCT values and biochemical or histologic assessment were weak to moderately strong (0.09-0.41; p < 0.0001-0.66). There was a weak correlation between the T2 values and cartilage proteoglycan (−0.32; p = 0.04). The correlation between T1ρ values and cartilage proteoglycan were moderately strong (−0.38; p < 0.05) while the strongest correlation was between the T1ρ values and histological assessment of cartilage with a correlation coefficient of 0.58 (p < 0.0001). These data suggest that T1ρ shows promise for possible utility in the translational study of cartilage health and warrants further development in this species.

show abstract

Comparison of Digital Radiography, Computed Tomography, and Magnetic Resonance Imaging Features in Canine Spontaneous Degenerative Stifle Joint Osteoarthritis

Chung

Lin

2023

Animals

View full text Add to dashboard Cite

Canine stifle joint osteoarthritis (OA) is characterized by damage and degeneration of the articular cartilage and subchondral bone, bony hypertrophy at the margins, and synovial joint membrane changes. Non-invasive imaging modalities, such as digital radiography (DR), computed tomography (CT), and magnetic resonance imaging (MRI), can be used to describe these changes. However, the value of MRI in diagnosing spontaneous canine OA and the comparison of different imaging modalities have seldom been addressed. This study compared multiple noninvasive imaging modalities in canine spontaneous stifle OA cases. Four client-owned dogs with five spontaneously affected OA stifle joints were recruited and underwent DR, CT, and MRI. Information on osteophytes/enthesophytes, ligament/tendon lesions, synovial effusion and membrane thickening, subchondral bone lesions, and meniscal and cartilage lesions were scored and compared. The results showed that MRI provides the most comprehensive and superior lesion detection sensitivity for ligament, meniscus, cartilage, and synovial effusions. DR provides adequate bony structure information, while CT provides the most delicate images of bony structure lesions. These imaging findings may provide further understanding of the disease and help clinicians draft a more precise treatment plan.

show abstract

Assessment of T2 Relaxation Times for Normal Canine Knee Articular Cartilage by T2 Mapping Using 1.5-T Magnetic Resonance Imaging

Cited by 4 publications

References 35 publications

Assessment of the usefulness of image reconstruction in the oblique and double-oblique sagittal planes for magnetic resonance imaging of the canine cranial cruciate ligament

Assessment of the usefulness of image reconstruction in the oblique and double-oblique sagittal planes for magnetic resonance imaging of the canine cranial cruciate ligament

T1ρ, T2 mapping, and EPIC‐µCT Imaging in a Canine Model of Knee Osteochondral Injury

Comparison of Digital Radiography, Computed Tomography, and Magnetic Resonance Imaging Features in Canine Spontaneous Degenerative Stifle Joint Osteoarthritis

Contact Info

Product

Resources

About