Assessment of Telomerase Reverse Transcriptase Single Nucleotide Polymorphism in Sleep Bruxism

Macek, Piotr; Więckiewicz, Mieszko; Poręba, Rafał; Gać, Paweł; Bogunia‐Kubik, Katarzyna; Dratwa, Marta; Wojakowska, Anna; Mazur, Grzegorz; Martynowicz, Helena

doi:10.3390/jcm11030525

Cited by 8 publications

(9 citation statements)

References 56 publications

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“…The offered explanation was that women are more vulnerable to the effects of unexpected, prolonged stress situations than men [59]. The results of two recent studies are suggesting that the prevalence does not vary between genders [60] or that the male gender was indicated as a risk factor [61].…”

Section: Discussionmentioning

confidence: 99%

Probable Bruxism and Psychological Issues among Dental Students in Serbia during the COVID-19 Pandemic

Kolak¹,

Pavlović²,

Aleksic³

et al. 2022

IJERPH

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The COVID-19 pandemic has drastically changed the routine way of life, having consequences in many segments of life, including dental practice and education. The aim of this study was to evaluate the frequency of probable bruxism in a sample of dental students in Serbia and to estimate the potential association between psychological factors related to the COVID-19 pandemic and the presence of bruxism. A cross-sectional study included 178 dental students in Serbia, who were interviewed using a specially-designed self-administered online questionnaire, which consisted of three sections, and after that, a clinical examination for the presence of bruxism symptoms in the oral cavity. Psychological status was evaluated using the Depression, Anxiety and Stress Scale-21 (DASS-21) and the Fear of COVID-19 Scale (FCV-19S). Saliva samples were taken to analyze salivary cortisol levels. The prevalence of probable bruxism was 34.8%. Respondents with probable bruxism had significantly higher DASS-21 and FCV-19S scores and mean values of salivary cortisol compared to non-bruxers. A history of COVID-19 infection, high stress, and fear of COVID-19 scores were associated with the presence of probable bruxism. The findings suggest that the COVID-19 pandemic has had a great psychological impact and impact on the presence and worsening of bruxism symptoms in a sample of dental students in Serbia.

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Section: Discussionmentioning

confidence: 99%

Probable Bruxism and Psychological Issues among Dental Students in Serbia during the COVID-19 Pandemic

Kolak¹,

Pavlović²,

Aleksic³

et al. 2022

IJERPH

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“…The etiology of bruxism is unclear, though recent stu dies reported genetic predisposition for sleep bruxism (SB). 8,9 Additionally, low plasma sodium concentration and inflammatory markers have been associated with SB. 10,11 Moreover, SB has been linked to the motor acti vity of the jaw muscles.…”

Section: Introductionmentioning

confidence: 99%

Investigation of the relationship between probable sleep bruxism, awake bruxism and temporomandibular disorders using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD)

Karaçay¹,

Şahbaz²

2023

Dent. Med. Probl.

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Background. The causal relationship between bruxism and temporomandibular disorders (TMD) is not clear.Objectives. The present study investigated which TMD are associated with probable sleep bruxism (SB) and awake bruxism (AB) according to the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD). The study further evaluated the association between probable SB and AB and TMD. Material and methods.A total of 143 patients were selected -bruxers (SB and AB) and non-bruxers. A diagnosis of probable bruxism was made after a physical examination and when the symptoms were detected. The patients were evaluated using DC/TMD. From among Axis I assessment instruments, the TMD Pain Screener, the Symptom Questionnaire and the Clinical Examination Form were used. Moreover, the Graded Chronic Pain Scale (GCPS) (v. 2), the Jaw Functional Limitation Scale-8 (JFLS-8), the Patient Health Questionnaire-4 (PHQ-4), and the Oral Behaviors Checklist (OBC) were applied within the scope of Axis II.Results. Diagnoses of muscle disorders and disk displacement with reduction were significantly more frequent in the SB and AB groups than in non-bruxers. A diagnosis of arthralgia was significantly more prevalent in the AB group than in non-bruxers. The JFLS-8 scores and the TMD Pain Screener scores were higher in the AB group than in the SB group and in non-bruxers. Distress levels, and the GCPS and OBC scores were higher in the SB and AB groups as compared to non-bruxers. The results of binary logistic regression analysis showed that only the OBC score was significantly higher in the TMD subgroup (OR (odds ratio) = 1.228; 95% CI (confidence interval): 1.014-1.488). Conclusions.Both SB and AB were associated with pain-related TMD and intra-articular joint disorders. The muscle disorders and disk displacement with reduction subtypes were associated with SB and AB. Unlike SB, AB was also associated with arthralgia. Bruxers (both SB and AB) displayed parafunctional habits. However, AB was associated with greater functional limitation of the jaw as compared to SB.

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“…Smardz et al [ 37 ] reported that males exhibited more severe SB than females. Macek et al [ 38 ] reported male sex as an independent risk factor for phasic SB. Guo et al [ 39 ] reported male sex as a risk factor for SB among children 0–12 years of age.…”

Section: Discussionmentioning

confidence: 99%

“…Second, we did not investigate single nucleotide polymorphisms (SNPs) related to SB. Some SNPs (rs2736100, SNP rs6313, rs2770304, rs4941573, and rs2770304) have been reported as risk factors for SB [ 38 , 45 ]. Third, since participants who belonged to the NSB group did not undergo electromyographic observation for SB, we did not compare differences in the numbers of episodes and bursts.…”

Section: Discussionmentioning

confidence: 99%

Nutrients Associated with Sleep Bruxism

Toyama

Ekuni

Fukuhara

et al. 2023

JCM

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Background: The purpose of the present research was to identify nutrients related to sleep bruxism and to establish a hypothesis regarding the relationship between sleep bruxism and nutrients. Methods: We recruited 143 Japanese university students in 2021 and assigned them to sleep bruxism (n = 58) and non-sleep bruxism groups (n = 85), using an identical single-channel wearable electromyography device. To investigate nutrient intakes, participants answered a food frequency questionnaire based on food groups. We assessed differences in nutrient intakes between the sleep bruxism and non-sleep bruxism groups. Results: Logistic regression modeling showed that sleep bruxism tended to be associated with dietary fiber (odds ratio, 0.91; 95% confidence interval, 0.83–1.00; p = 0.059). In addition, a subgroup analysis selecting students in the top and bottom quartiles of dietary fiber intake showed that students with sleep bruxism had a significantly lower dietary fiber intake (10.4 ± 4.6 g) than those without sleep bruxism (13.4 ± 6.1 g; p = 0.022). Conclusion: The present research showed that dietary fiber intake may be related to sleep bruxism. Therefore, we hypothesized that dietary fiber would improve sleep bruxism in young adults.

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Assessment of Telomerase Reverse Transcriptase Single Nucleotide Polymorphism in Sleep Bruxism

Cited by 8 publications

References 56 publications

Probable Bruxism and Psychological Issues among Dental Students in Serbia during the COVID-19 Pandemic

Probable Bruxism and Psychological Issues among Dental Students in Serbia during the COVID-19 Pandemic

Investigation of the relationship between probable sleep bruxism, awake bruxism and temporomandibular disorders using the Diagnostic Criteria for Temporomandibular Disorders (DC/TMD)

Nutrients Associated with Sleep Bruxism

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