Assessment of the Accuracy and Reproducibility of RV Volume Measurements by CMR in Congenital Heart Disease

Clarke, Christopher J.; Gurka, Matthew J.; Norton, Patrick T.; Kramer, Christopher M.; Hoyer, Andrew W.

doi:10.1016/j.jcmg.2011.05.007

Cited by 75 publications

(54 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For each subject, breath-held segmented 2D bSSFP cine images were acquired in the 4-chamber orientation with a stack of images in the short axis orientation covering the entire RV. The use of short axis images was based on both clinical experience and recent data showing statistical equivalence in the measurement of RV parameters using short axis or axial planes [24]. For each 2D image, data was acquired using three different imaging techniques (detailed imaging parameters are delineated in Table 1):…”

Section: Cmr Protocolmentioning

confidence: 99%

Right ventricular assessment at cardiac MRI: initial clinical experience utilizing an IS-SENSE reconstruction

Bogachkov¹,

Ayache²,

Allen³

et al. 2016

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

Cardiac MR is considered the gold standard in assessing RV function. The purpose of this study is to evaluate the clinical utility of an investigational iterative reconstruction algorithm in the quantitative assessment of RV function. This technique has the potential to improve the clinical utility of CMR in the evaluation of RV pathologies, particularly in patients with dyspnea, by shortening acquisition times without adversely influencing imaging performance. Segmented cine images were acquired on 9 healthy volunteers and 29 patients without documented RV pathologies using conventional GRAPPA acquisition with factor 2 acceleration (GRAPPA 2), a spatio-temporal TSENSE acquisition with factor 4 acceleration (TSENSE 4), and iteratively reconstructed Sparse SENSE acquisition with factor 4 acceleration (IS-SENSE 4). 14 subjects were re-analyzed and intraclass correlation coefficients (ICC) were calculated and Bland-Altman plots generated to assess agreement. Two independent reviewers qualitatively scored images. Comparison of acquisition techniques was performed using univariate analysis of variance (ANOVA). Differences in RV EF, BSA-indexed ESV (ESVi), BSA-indexed EDV (EDVi), and BSA-indexed SV (SVi) were shown to be statistically insignificant via ANOVA testing. R(2) values for linear regression of TSENSE 4 and IS-SENSE 4 versus GRAPPA 2 were 0.34 and 0.72 for RV-EF, and 0.61 and 0.76 for RV-EDVi. ICC values for intraobserver and interobserver quantification yielded excellent agreement, and Bland-Altman plots assessing agreement were generated as well. Qualitative review yielded small, but statistically significant differences in image quality and noise between TSENSE 4 and IS-SENSE 4. All three techniques were rated nearly artifact free. Segmented imaging acquisitions with IS-SENSE reconstruction and an acceleration factor of 4 accurately and reliably quantitates RV systolic function parameters, while maintaining image quality. TSENSE-4 accelerated acquisitions showed poorer correlation to standard imaging, and inferior interobserver and intraobserver agreement. IS-SENSE has the potential to shorten cine acquisition times by 50 %, improving imaging options in patients with intermittent arrhythmias or difficulties with breath holding.

show abstract

Section: Cmr Protocolmentioning

confidence: 99%

Right ventricular assessment at cardiac MRI: initial clinical experience utilizing an IS-SENSE reconstruction

Bogachkov¹,

Ayache²,

Allen³

et al. 2016

Int J Cardiovasc Imaging

View full text Add to dashboard Cite

show abstract

“…To cover both ventricles from base to apex, a stack of images is required usually in the short-axis plane. Some authors, however, reported more accurate RV volume measurements in CHD when using images acquired in an axial orientation 16. In adult patients with PH, a large RV volume, a reduced RV ejection fraction and a reduced LV volume as evaluated by CMR have been repeatedly identified as independent predictors of mortality and treatment failure 17 18.…”

Section: Cardiac Magnetic Resonancementioning

confidence: 99%

Multimodality imaging in congenital heart disease-related pulmonary arterial hypertension

D′Alto

Dimopoulos

Budts

et al. 2016

Heart

View full text Add to dashboard Cite

Pulmonary arterial hypertension (PAH) in adult patients with congenital heart disease (CHD) is associated with increased morbidity and mortality. The present review aims to discuss the clinical applications of invasive and non-invasive diagnostic modalities and to describe the strengths and weaknesses of each technique. Chest radiograph is an inexpensive investigation providing information on pulmonary arterial and hilar dilatation, pruning of peripheral pulmonary arteries and cardiomegaly. Transthoracic two-dimensional and Doppler echocardiography is the most widely used imaging tool. It provides information on cardiac anatomy and an estimate of haemodynamics and biventricular remodelling and function. In addition, echocardiography is valuable in assessing prognosis and monitoring the efficacy of therapy. Structural and functional changes associated with CHD-PAH, mainly affecting the right ventricle and pulmonary circulation, may represent an ideal target for evaluation with cardiac magnetic resonance. This non-invasive imaging modality has a low biological impact. CT plays an important role for patients with limited echocardiographic windows and those who are unable to undergo MRI (claustrophobia, poor compliance, presence of a pacemaker/implantable cardioverter defibrillator). It is the modality of choice for detailed assessment of pulmonary vessel obstruction or thrombosis. Finally, heart catheterisation remains the gold standard for diagnosing and confirming PAH in patients with CHD and for shunt evaluation. The diagnostic assessment of CHD-PAH requires great expertise and a deep knowledge of both CHD and PAH pathophysiology and should take place in a tertiary centre, where multiple data can be appropriately integrated and applied clinically.

show abstract

“…Studies by Hudsmith et al 16 and Grothues et al 15 reported similar interobserver coefficients of variations for RV measurements. Clarke et al 17 compared the observer variability of RV volume measurements between images obtained in the short-axis plane versus the axial plane in 50 patients with CHD. The intra- and interobserver reliability of RV end-diastolic volume, end-systolic volume, and stroke volume measurements was excellent for both contouring methods.…”

Section: Cmr Is the Gold Standard For Noninvasive Measurements Of Rv mentioning

confidence: 99%

Is MRI the Preferred Method for Evaluating Right Ventricular Size and Function in Patients With Congenital Heart Disease?

Geva

2014

Circ: Cardiovascular Imaging

116

View full text Add to dashboard Cite

Assessment of the Accuracy and Reproducibility of RV Volume Measurements by CMR in Congenital Heart Disease

Cited by 75 publications

References 31 publications

Right ventricular assessment at cardiac MRI: initial clinical experience utilizing an IS-SENSE reconstruction

Right ventricular assessment at cardiac MRI: initial clinical experience utilizing an IS-SENSE reconstruction

Multimodality imaging in congenital heart disease-related pulmonary arterial hypertension

Is MRI the Preferred Method for Evaluating Right Ventricular Size and Function in Patients With Congenital Heart Disease?

Contact Info

Product

Resources

About