Assessment of the analgesic effects of ketoprofen in ducks anesthetized with isoflurane

Abstract

Ketoprofen reduced the increases in heart and respiratory rates associated with application of a noxious stimulus in spontaneously breathing adult Mallard ducks anesthetized with isoflurane delivered at approximately 2.9%, suggesting that ketoprofen had analgesic effects in these ducks. The onset of analgesic effects may be longer than 30 minutes in some ducks.

Pharmacokinetics of meloxicam after intravenous, intramuscular, and oral administration of a single dose to Hispaniolan Amazon parrots (Amazona ventralis)

“…4,5 However, there may be considerable differ-ences among species with regard to the relative COX-1 or COX-2 selectivity of certain drugs as well as differences in selectivity between in vivo and in vitro pharmacodynamic assays. 4,5 Pharmacokinetics and toxicological effects of NSAIDs, such as meloxicam, sodium salicylate, and flunixin, have been evaluated in a few avian species, including chickens, 4,[6][7][8][9] mallard ducks, 9,10 vultures, [11][12][13] psittacine birds, 14,15 Coturnix quail (Coturnix japonica), 16 pigeons, 9,17 ostriches, and turkeys. 9 The relative expression of COX-1 and COX-2 differs among avian species.…”

Pharmacokinetics of ketoprofen in Japanese quail (Coturnix japonica)

“…Lisa Tell, Department of Medicine and Epidemiology, University of California at Davis, One Shields Avenue, Davis, CA 95616-8747, USA. E-mail: latell@ucdavis.edu Pharmacokinetics of ketoprofen have been established in numerous mammalian species; however, no published pharmacokinetic data exist for avian species, although some studies have evaluated the pharmacodynamics (Machin et al, 2001) and analgesic effects (Machin & Livingston, 2002) of this nonsteroidal anti-inflammatory drug in ducks. Ketoprofen is a chiral compound that exists as two enantiomers, R()) and S(+) ketoprofen.…”

Pino ósseo homólogo conservado em glicerina a 98% e hemicerclagem com fio poliglactina 910 na osteossíntese umeral de pombos domésticos

“…O uso de antiinflamatórios é indicado em qualquer procedimento cirúrgico em aves (MARCHIN, 2002) Na avaliação clínica, foram observados movimentos normais do membro e sua posição anatômica, logo após a cirurgia. Para LEVITT (1989), o método de fixação deve permitir o uso normal do membro no pós-operatório, pois pequenos movimentos minimizam a atrofia e ajudam a cicatrização.…”