Assessment of the dentin‐pulp complex response to caries by ADC mapping

Vidmar, Jernej; Cankar, Ksenija; Németh, L; Serša, Igor

doi:10.1002/nbm.2770

Cited by 9 publications

(5 citation statements)

References 30 publications

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“…Nevertheless, the ACAD profile with standard deviations always fell within the range of those in NCAD, and the type of caries-affected dentin was not a statistically significant factor when comparing mineral density at different lesion levels. It should be noted that the NCAD lesions greatly vary in depth depending on the activity of the lesion and the time that dentin was subjected to the caries process; indeed caries may affect the whole thickness of dentin from dentinenamel junction through to the pulp 17) . The ACAD in the current study was compared to NCAD superficially (up to 150 µm), because in terms of the bonding interface with restorative materials, only this zone plays a role.…”

Section: Discussionmentioning

confidence: 99%

Mineral density, morphology and bond strength of natural versus artificial caries-affected dentin

et al. 2013

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This study aimed to investigate an artificial caries-affected dentin (ACAD) model for in vitro bonding studies in comparison to natural caries-affected dentin (NCAD) of human teeth. ACAD was created over 7 days in a demineralizing solution. Mineral density (MD) at different depth levels (0-150 µm) was compared between NCAD and ACAD by transverse microradiography. Micro-tensile bond strengths (µTBS) of two two-step self-etch adhesives to sound dentin, NCAD and ACAD were evaluated. Caries-affected dentin type was not a significant factor when comparing MD at different lesion levels (p>0.05). Under SEM, the dentinal tubules appeared occluded with crystal logs 1-2 µm in thickness in the NCAD; whereas they remained open in the ACAD. The µTBS to caries-affected dentin was lower than sound dentin, but was not affected by the type of caries (p>0.05). In spite of their different morphologies, the ACAD model showed similar MD and µTBS compared to NCAD.

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Section: Discussionmentioning

confidence: 99%

Mineral density, morphology and bond strength of natural versus artificial caries-affected dentin

et al. 2013

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“…Its use produced a nearly perfect linear relation to ICDAS scores, i.e. the higher the average ADC value, the lower the ICDAS score [Vidmar et al, 2012]. It must also be noted that the time involved for ADC mapping -equal to one and a half hours in our study -is still too long for in vivo use.…”

Section: Discussionmentioning

confidence: 85%

“…Before extraction all caries lesions were clinically examined using the visual-tactile method and recorded as active following the scores and criteria used by Ekstrand et al [1998]. The teeth were immersed in a physiological solution (pH ≈ 7.4) immediately after extraction and subsequently stored in a neutral buffered 10% formalin solution (Sigma-Aldrich, Germany) at 8 ° C in order to avoid autolysis in the pulp [Vidmar et al, 2012]. In order to prevent dental pulp desiccation during long scanning time as well as to visualize the tooth surface, the teeth were coated with the two-component silicone dental impression material Exaflex ® (GC, Japan) prior to MR acquisition.…”

Section: Human Teethmentioning

confidence: 99%

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Discrimination between Intact and Decayed Pulp Regions in Carious Teeth by ADC Mapping

et al. 2014

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The aim of this study was to evaluate an advanced magnetic resonance imaging (MRI) method, apparent diffusion coefficient (ADC) mapping, in the functional assessment of carious teeth. 38 extracted human teeth with scores of 0, 3 and 6 according to International Caries Detection and Assessment System (ICDAS) criteria were screened and subsequently analyzed by MRI at 2.35 T. Histology sectioning of teeth was used for the gold standard by analyzing two extreme cases (intact and severely decayed). ADC maps of the same teeth were calculated from corresponding diffusion-weighted images and used to obtain ADC distributions along dental pulp as functions of the relative pulp length measured from the occlusal pulp side. The measured distributions were analyzed for the best fit by a four-parameter three-segment linear regression model for ADC distribution along the pulp. MRI results were in good agreement with findings in histological sections of identical teeth. The best fit model parameters, relative decayed region depth, relative transition region width and ADC values of intact and decayed pulp tissue, showed statistically significant differences between the ADC values of intact and decayed pulp tissue (1.0 × 10^-9 m²/s vs. 0.74-0.89 × 10^-9 m²/s) and the relative decayed region depth progressing with ICDAS score (3 vs. 46% with ICDAS 3 vs. ICDAS 6). The results of this feasibility study confirmed relevance of ADC mapping for the discrimination and localization of intact and decayed regions in dental pulps of carious teeth.

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“…4 , 22 One of most recent MRI studies demonstrated that caries affected also dental pulp by changing its diffusion properties. 23 …”

Section: Introductionmentioning

confidence: 99%

Human tooth pulp anatomy visualization by 3D magnetic resonance microscopy

Sustercic¹,

Serša²

2012

Radiology and Oncology

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BackgroundPrecise assessment of dental pulp anatomy is of an extreme importance for a successful endodontic treatment. As standard radiographs of teeth provide very limited information on dental pulp anatomy, more capable methods are highly appreciated. One of these is 3D magnetic resonance (MR) microscopy of which diagnostic capabilities in terms of a better dental pulp anatomy assessment were evaluated in the study.Materials and methodsTwenty extracted human teeth were scanned on a 2.35 T MRI system for MR microscopy using the 3D spin-echo method that enabled image acquisition with isotropic resolution of 100 μm. The 3D images were then post processed by ImageJ program (NIH) to obtain advanced volume rendered views of dental pulps.ResultsMR microscopy at 2.35 T provided accurate data on dental pulp anatomy in vitro. The data were presented as a sequence of thin 2D slices through the pulp in various orientations or as volume rendered 3D images reconstructed form arbitrary view-points. Sequential 2D images enabled only an approximate assessment of the pulp, while volume rendered 3D images were more precise in visualization of pulp anatomy and clearly showed pulp diverticles, number of pulp canals and root canal anastomosis.ConclusionsThis in vitro study demonstrated that MR microscopy could provide very accurate 3D visualization of dental pulp anatomy. A possible future application of the method in vivo may be of a great importance for the endodontic treatment.

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Assessment of the dentin‐pulp complex response to caries by ADC mapping

Cited by 9 publications

References 30 publications

Mineral density, morphology and bond strength of natural versus artificial caries-affected dentin

Mineral density, morphology and bond strength of natural versus artificial caries-affected dentin

Discrimination between Intact and Decayed Pulp Regions in Carious Teeth by ADC Mapping

Human tooth pulp anatomy visualization by 3D magnetic resonance microscopy

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