Assessment of the effect of monohydroxy alcohols, unsaturated fatty acids, organophosphate compounds on the enzymatic ATP-hydrolysis in the cell membranes of the smooth muscle of rat colon

Kaplia, A. A.; Мидык, С. В.; Khyzhnyak, S. V.

doi:10.15407/ubj90.04.064

Ukr.Biochem.J.

2018

DOI: 10.15407/ubj90.04.064

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Assessment of the effect of monohydroxy alcohols, unsaturated fatty acids, organophosphate compounds on the enzymatic ATP-hydrolysis in the cell membranes of the smooth muscle of rat colon

A. A. Kaplia¹,

С. В. Мидык²,

S. V. Khyzhnyak³

Abstract: The differences of the structural-functional stability of ATP-hydrolases

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2022

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Cited by 1 publication

References 30 publications

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Fatty acid profile of the liver lipids under acute fungicide action and intake of a biologically active preparation in rats

Khyzhnyak¹,

Мидык²,

Velinska³

et al. 2022

Ukr.Biochem.J.

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The widespread use of fungicides in agriculture leads to a negative consequences for both humans and the environment. The acute effect of fungicides containing tebuconazole alone or in combination with triadimefon on fatty acid (FAs) composition of the total lipids in the liver of rats was studied. FAs content was analyzed by gas chromatography with the use of flame ionization detector. The results obtained indicate that the acute effect of triazole fungicides one-time oral administration to rats is characterized by toxic reactions and is accompanied by the total liver lipids FAs profile redistribution, similar for the studied fungicides. In particular, the reduction in the total content of monounsaturated FAs (by 26% – 37%) and in the ω3/ω6 ratio was observed. It was demonstrated that the subsequent two-week introduction of the preparation based on Milk thistle seeds oil extract had a positive effect and improved the FAs profile of lipids in dynamics after fungicide intake. Keywords: fatty acids, fungicides, Milk thistle seeds extract, rat liver lipids, triazoles

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Fatty acid profile of the liver lipids under acute fungicide action and intake of a biologically active preparation in rats

Khyzhnyak¹,

Мидык²,

Velinska³

et al. 2022

Ukr.Biochem.J.

Self Cite

View full text Add to dashboard Cite

show abstract

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Assessment of the effect of monohydroxy alcohols, unsaturated fatty acids, organophosphate compounds on the enzymatic ATP-hydrolysis in the cell membranes of the smooth muscle of rat colon

Abstract: The differences of the structural-functional stability of ATP-hydrolases

Cited by 1 publication

References 30 publications

Fatty acid profile of the liver lipids under acute fungicide action and intake of a biologically active preparation in rats

Fatty acid profile of the liver lipids under acute fungicide action and intake of a biologically active preparation in rats

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