Assessment of the Effect of the Use of Laser Light or Dantrolene on Facial Muscle Under Occlusal Wear: A Raman Spectroscopic Study in a Rodent Model

Lisboa, Marcio Vieira; Lopes, Cibelle Barbosa; Rocha, Rosana Moreira da; Ramos, Thaís Andrade; Abreu, Igor Dourado Neto de; Cangussú, Maria Cristina Teixeira; Pinheiro, António Luiz Barbosa; Santos, Jean Nunes dos

doi:10.1089/pho.2009.2614

Cited by 1 publication

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“…Based on these features, it is possible to state that administration of skeletal muscle relaxant may prevent the occurrence of ultra-morphologic alterations. However, as there were no statistical differences between groups I, II, II and IV, other features especially those related to muscle biochemistry should be further investigated (Lisboa et al, 2010).…”

Section: Resultsmentioning

confidence: 99%

Influence of Laser Therapy and Muscle Relaxant on the Masseter Muscle under Occlusal Wear: An Ultrastructural Study

et al. 2012

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SUMMARY:The aim of this study was to analyze the influence of low-intensity laser therapy and muscle relaxant in the characteristic ultra structural masseter muscle occlusal wear. Animals and Methods: 40 male Wistar rats were randomly divided into four groups: the control group (GI), occlusal wear (G-II), laser occlusal wear (G-III), and the muscle relaxant occlusal wear (G-IV). Under general anesthesia given intraperitoneally, animals in groups II, III and IV had unilateral amputation of upper and lower molar cusps to simulate an occlusal wear situation. The masseter muscle G-III received laser therapy (830nm, 4J/cm2, 40mW, f ~ 2mm) and the procedure was subsequently repeated every other day for 14/30 days. G-IV animals were treated with daily injection of dantrolene ® (2.5 mg / kg in 0.5 ml of H 2 O). From 24 hours after the elimination peak. The animals were euthanized with an overdose of anesthesia on days 14 and 30 after the removal of the cusps and the ipsilateral masseter muscle was excised and divided in two, one half was routinely processed for light microscopy and other for electron microscopy. There was no statistical difference between each experimental group and the control and between periods in each experimental group. However, the muscle fibers in the G-II showed the most pronounced changes. There is no causal relationship between muscles fibers injuries and occlusion and, despite signs of muscular tissue injury were more evident in the occlusal wear group. Results indicates a moderate action of laser therapy and muscle relaxants in skeletal muscle.

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Section: Resultsmentioning

confidence: 99%

Influence of Laser Therapy and Muscle Relaxant on the Masseter Muscle under Occlusal Wear: An Ultrastructural Study

et al. 2012

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Assessment of the Effect of the Use of Laser Light or Dantrolene on Facial Muscle Under Occlusal Wear: A Raman Spectroscopic Study in a Rodent Model

Abstract: Occlusal wear did not caused morphologic alterations in the masseter muscle but resulted in changes of the levels of CaP(i) that were less compromising when the laser light was used.

Cited by 1 publication

References 54 publications

Influence of Laser Therapy and Muscle Relaxant on the Masseter Muscle under Occlusal Wear: An Ultrastructural Study

Influence of Laser Therapy and Muscle Relaxant on the Masseter Muscle under Occlusal Wear: An Ultrastructural Study

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