Fine particulate matter (PM
2.5
) is the leading environmental risk factor that requires regular monitoring and analysis for effective air quality management. This work presents the variability, trend, and exceedance analysis of PM
2.5
measured at US Embassy and Consulate in five Indian megacities (Chennai, Kolkata, Hyderabad, Mumbai, and New Delhi) for six years (2014–2019). Among all cities, Delhi is found to be the most polluted city followed by Kolkata, Mumbai, Hyderabad, and Chennai. The trend analysis for six years for five megacities suggests a statistically significant decreasing trend ranging from 1.5 to 4.19 μg/m
3
(2%–8%) per year. Distinct diurnal, seasonal, and monthly variations are observed in the five cities due to the different site locations and local meteorology. All cities show the highest and lowest concentrations in the winter and monsoon months respectively except for Chennai which observed the lowest levels in April. All the cities consistently show morning peaks (~08: 00–10:00 h) and the lowest level in late afternoon hours (~15:00–16:00 h). We found that the PM
2.5
levels in the cities exceed WHO standards and Indian NAAQS for 50% and 33% of days in a year except for Chennai. Delhi is found to have more than 200 days of exceedances in a year and experiences an average 15 number of episodes per year when the level exceeds the Indian NAAQS. The trends in the exceedance with a varying threshold (20–380 μg/m
3
) suggest that not only is the annual mean PM
2.5
decreasing in Delhi but also the number of exceedances is decreasing. This decrease can be attributed to the recent policies and regulations implemented in Delhi and other cities for the abatement of air pollution. However, stricter compliance of the National Clean Air Program (NCAP) policies can further accelerate the reduction of the pollution levels.