Assessment of the Efficacy of Cryolipolysis on Saddlebags: A Prospective Study of 53 Patients

Adjadj, Lucille; SidAhmed-Mezi, Mounia; Mondoloni, Marine; Meningaud, Jean Paul; Hersant, Barbara

doi:10.1097/prs.0000000000003433

Cited by 26 publications

(17 citation statements)

References 20 publications

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“…Savacini et al observed similar results when cryolipolysis was used for esthetic flank contouring, 25 including a significant subcutaneous fat layer reduction, confirmed in further studies of the submental region (of 2.0 mm), the inner thighs (of 2.8 mm), the lateral thighs (of 2.6 mm), and the saddlebacks. 12,16,[25][26][27] Unfortunately, there is no comparative data available measuring the subcutaneous fat layer reduction after flap contouring by liposuction or partial excision.…”

Section: Discussionmentioning

confidence: 99%

From Esthetic Medicine to Optimizing Reconstructive Outcome: A Feasibility Trial on Secondary Refinement of Fasciocutaneous Anterolateral Thigh Flaps with Cryolipolysis

Nagel

Rauh

Siegwart

et al. 2022

J Reconstr Microsurg

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Background Free adipocutaneous anterolateral thigh (ALT) flaps have evolved as workhorse flaps to reconstruct complex, multicompound defects. While coverage is safely achieved, flaps may remain bulky. As a standard of care, flaps are refined with liposuction, partial excision, or combination of both. Cryolipolysis is widely used for fat reduction in esthetic medicine. This pilot comparative study analyses whether cryolipolysis may serve as a safe alternative method to effectively reduce volume in fasciocutaneous flaps. Moreover, patients' satisfaction with the procedure is evaluated. Methods In this single-center, retrospective, interventional comparative cohort study, 10 patients with free subfascial ALT flaps for distal extremity reconstruction underwent cryolipolysis (60 minutes, −9°C). Circumference of the extremities and subcutaneous fat thickness were determined before (T1) and 12 weeks (T2) after cryolipolysis. Patient satisfaction was evaluated with a questionnaire of Likert's scale questions. Duration of hospital stay, intervention time, costs, and possible complications were analyzed and compared with surgical flap contouring (n = 12). Results All patients undergoing cryolipolysis were male, with a median age of 52 years without arterial disease-like state or deep vein thrombosis (DVT). At T2, a significant reduction of circumference of 1.8 ± 0.9 cm (p < 0.001) and subcutaneous fat layer of 7.7 ± 3.0 mm (p < 0.0001) was recorded. Overall, 90% of the patients were satisfied with the result. Cryolipolysis was well tolerated. One patient developed a second-degree frostbite which healed without further intervention. Cryolipolysis proofed to be as safe as surgical flap contouring. Hospital stay was significantly shorter (p < 0.01) and personal resources were spared when flap contouring was performed with cryolipolysis. Conclusion This is a novel application of evolving body-contouring cryolipolysis from esthetic medicine into optimizing outcomes in reconstructive surgery. Cryolipolysis has been shown to be relatively safe and effective to reduce ALT's volume with high patients' satisfaction. This successful pilot study encourages further investigation with a prospective randomized control trial.

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Section: Discussionmentioning

confidence: 99%

From Esthetic Medicine to Optimizing Reconstructive Outcome: A Feasibility Trial on Secondary Refinement of Fasciocutaneous Anterolateral Thigh Flaps with Cryolipolysis

Nagel

Rauh

Siegwart

et al. 2022

J Reconstr Microsurg

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“…The abdomen and flanks were the selected areas for treatment. According to one study, cryolipolysis has been shown to be effective in reducing localized subcutaneous fat from various anatomical areas, namely, the abdomen, flanks, arms, back, knees, and inner thighs 35 . However, Oliveira et al, state that although most studies reveal a significant reduction in fat in all areas evaluated, it is not yet known for sure which ones respond better to treatment, since this reduction may be dependent on factor, such as the vascularization and local cytoarchitecture as well as the metabolic activity of the adipose tissue deposits in question.…”

Section: Discussionmentioning

confidence: 99%

Application of cryolipolysis in adipose tissue: A systematic review

Resende

Noites

Amorim

2022

J of Cosmetic Dermatology

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Background Cryolipolysis is characterized by localized and controlled cooling of the subcutaneous adipose tissue, in a non‐invasive way, causing a localized panniculitis, followed by adipocyte death by apoptosis and, consequently, a decrease in adipose tissue in the treated area. Aim(s) To evaluate the scientific evidence and methodological qualities about effects, adverse reactions, and level of satisfaction of cryolipolysis for the reduction of subcutaneous adipose tissue. Methods A systematic review was carried out according to the PRISMA recommendation. Searches were conducted in different databases. We included studies that used a randomized control and self‐control design and were carried out in humans. Articles published in English and Portuguese were screened, with no time limit regarding the year of publication. The methodological quality of the studies was assessed using the Cochrane Rob2 scale. Results Of 381 articles, seven were considered eligible for inclusion. After applying the Cochrane Rob2 scale, five studies were included in the final sample. Most studies showed significant results for cryolipolysis in reducing localized fat. The incorporation of a dietary program into the treatment was shown to contribute to a significant improvement in the lipid profile and liver enzymes, which does not happen when cryolipolysis is applied in isolation. Rare adverse effects have been identified, but never persisting beyond a month. Conclusions Cryolipolysis is an effective technique for reducing localized fat, safe, and well tolerated, with most participants satisfied at the end of the treatment. However, more randomized controlled studies should be carried out, since there is a limited number of articles with good methodological quality.

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“…Coleman et al 25 used ultrasound to evaluate the fat layer thickness after cryolipolysis. Recently, Adjadj et al 27 used ultrasound to measure the decrease in fat thickness after cryolipolysis. Ultrasound imaging can quantitate changes in buttock thickness after fat transfer.…”

Section: Discussionmentioning

confidence: 99%

“… 23 , 24 This device has also been used to measure decreases in thickness after nonsurgical fat reduction including cryolipolysis. 25 – 27 Other novel applications include evaluation of facial hyaluronic acid injection and subcutaneous thickness after botulinum toxin injection. 28 – 30 …”

Section: Introductionmentioning

confidence: 99%