Background: Royal jelly is a bee's milky secretion extracted from a worker honey bee with potent antimicrobial, antioxidant, and antiinflammatory properties. It is effective in periodontal disease.
Methodology:In this randomised controlled clinical trial, 30 chronic periodontitis patients with at least 10 teeth with probing pocket depth up to 5-7 mm were selected for the study by simple random sampling technique and were subdivided into three groups: Group 1 (n = 10; scaling and root planing (SRP) + royal jelly irrigation), Group 2 (n = 10; scaling and root planing + saline irrigation), Group 3 (n = 10; scaling and root planing + distilled water irrigation). Clinical periodontal parameters like plaque index, gingival index, and probing pocket depth were measured at baseline and after 45 days.Results: Descriptive analysis was used for the distribution of variables in each group at both the baseline and 45th day for further statistical analysis and comparison. The clinical parameters compared within all three groups at baseline and 45th day by ANOVA were not statistically significant at different time intervals (p > 0.05). For the royal jelly group, the results were statistically significant for all clinical indices at baseline and 45th day. It was found to be equally effective as saline irrigation (p < 0.005) and more effective than distilled water (p > 0.005) as analysed by paired t test.
Conclusion:Royal jelly agents, as an irrigant, can act as a better treatment modality in periodontal disease management due to their abundant clinical properties.