Assessment of the Efficacy of Viagra^® (Sildenafil Citrate) Using the Erectile Dysfunction Inventory of Treatment Satisfaction (Edits)

Abstract

Treatment satisfaction is a predictor of long-term compliance in patients with erectile dysfunction (ED). We assessed patient satisfaction with and efficacy of Viagra^® (sildenafil citrate) using the Erectile Dysfunction Inventory of Treatment Satisfaction (EDITS) and 3 global efficacy questions. Twenty-nine men with ED who had completed a prior study of MUSE^® (alprostadil) versus Caverject^® (alprostadil) took a 50-mg dose of Viagra 1 h preceding intercourse. Efficacy and patient satisfaction with Viagra were high. Satisfaction as measured by EDITS was highly correlated to patients’ final ED treatment choice. This correlation could make EDITS useful in identifying long-term patient satisfaction, and thus of considerable clinical benefit.

Is there a role for bilateral peak systolic velocity readings in a penile duplex ultrasound?

“…Although correlation was expected (Cappelleri, Tseng, Stecher, & Goldstein, 2018), it had not been demonstrated until now. The EDITS questionnaire score results were within the range of what is expected of a ED population treated with sildenafil citrate (Lewis et al, 2001;Sadeghi-Nejad, Lim, Long, & Gilhooly, 2003). A slightly better result was expected, as all patients started 100 mg of sildenafil citrate, and roughly, half of the patients probably had a psychogenic aetiology for ED, which is well above the previously cited research.…”

Osteoporosis medication profile preference: results from the PREFER‐US study

“…comparing different inhalation therapies), 46 diabetes (e.g. comparing different modes of insulin delivery), 47 erectile dysfunction, 48 GERD, 49 glaucoma, 50 HIV, 51 insomnia, 52 irritable bowel syndrome, 53 migraine 20 and osteoporosis (e.g. comparing drugs of the same class differing in dosing frequency 23,54–56 ).…”

The Treatment of Erectile Dysfunction study: focus on treatment satisfaction of patients and partners

“…(The percentages do not add to 100% because some patients in each group preferred treatments other than sildenafil or tadalafil, or preferred to discontinue treatment.) In a previous study comparing sildenafil with alternative ED therapies, treatment satisfaction as measured by EDITS index scores was highly correlated with patients’ final treatment preference [30]. Patients with ED who chose sildenafil therapy had a mean EDITS index score of 72, compared with a mean of 40 in patients choosing alternative treatments, including intracavernosal injection therapy [30].…”

“…The EDITS and other assessment indices (e.g. International Index of Erectile Function, Sexual Encounter Profile diary) were used to show improved treatment satisfaction of patients with ED and/or their partners with sildenafil [16,28–30]; increased intercourse satisfaction and overall satisfaction in men with ED treated with vardenafil [31,32]; and improved sexual satisfaction and overall satisfaction with tadalafil among ED patients with varying degrees of ED severity, and their partners [33–35].…”

“…In a previous study comparing sildenafil with alternative ED therapies, treatment satisfaction as measured by EDITS index scores was highly correlated with patients’ final treatment preference [30]. Patients with ED who chose sildenafil therapy had a mean EDITS index score of 72, compared with a mean of 40 in patients choosing alternative treatments, including intracavernosal injection therapy [30]. Previous open‐label studies showed significantly higher EDITS index scores for sildenafil (vs intracavernosal injection therapy) in patients changing to sildenafil [36,37].…”