Acoustic emission (AE) is well suited for the real-time monitoring and detection of damage in reinforced concrete structures. In this study, loading/unloading cycles up to failure were applied on three different full-scale beams, each with varying defect morphologies. An intensity analysis method was employed to assess the damage sensitivities of the defective structures under stress conditions. Specifically, the calm ratio, load ratio, severity, and historical index were identified as statistical parameters that can provide global information on the damage level. Consequently, they can be easily used as damage evolution indexes for reinforced concrete structures. Correlations between these parameters were investigated to better discriminate between their potentials and identify critical levels that might not be evident using parametric analysis. The AEI chart helps locate damaging areas, aiding focused repairs. For defected beams with broken strands, at low load, HI and SI fall in zone B (damage detected). At cycles 4 and 6, with significant deflection, they fall into a critical zone, E (severe damage). Comparing post-tensioned beams revealed defects correlating with damage susceptibility. B3 beams with diffused defects displayed high activity at higher loads. Applying a load–calm ratio chart, initial minor damage worsened progressively. Severe damage was prominent in defective B2 and B3 beams, reaching zone 3. The variation in the acquired parameters over time can then be considered as an affordable and reliable indicator of damage progression.