Assessment of the mean time in the therapeutic INR range and the SAME-TT2R2 score in patients with atrial fibrillation and cognitive impairment

Gorzelak-Pabiś, Paulina; Zyzak, Sandra; Krewko, Łukasz; Broncel, Marlena

doi:10.20452/pamw.3475

Cited by 9 publications

(19 citation statements)

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“…The SAMe-TT 2 R 2 score has been assessed in 15 exclusively AF cohorts, [174][175][176][177][178][179][180][181][182][183][184][185] with six 175,177,179,180,183,186 reporting its predictive ability to forecast good or poor anticoagulation control, with c-statistics ranging from 0.56 180 to 0.72. 172 However, these cohorts were predominantly elderly, Western (white) populations, and its predictive ability in non-Western populations has relatively limited data as only 3 studies have assessed it, 174,175 with only 1 reporting c-statistics (c-statistic, 0.54; 95% CI, 0.52-0.57).…”

Section: Anti-thrombotic Therapy and Other Approaches For Stroke Prevmentioning

confidence: 99%

Antithrombotic Therapy for Atrial Fibrillation

Lip

Banerjee

Boriani

et al. 2018

Chest

772

328

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Section: Anti-thrombotic Therapy and Other Approaches For Stroke Prevmentioning

confidence: 99%

Antithrombotic Therapy for Atrial Fibrillation

Lip

Banerjee

Boriani

et al. 2018

Chest

772

328

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“…With the exception of three [6][7][8] all were performed in AF patients. 2,5,[9][10][11][12][13][14][15][16][17][18][19][20][21][22] Most studies (n=11) [5][6][7]11,14,17,[19][20][21][22] were performed prospectively, with follow-up duration ranging from six-months 17 to 4.7 years. 15 The number of participants included in VTE cohorts ranged from 135 6 to 1943 8 and between 104 14 to 8120 21 in studies on AF patients.…”

Section: Searches Identified 166 Citations After Removal Of Duplicatmentioning

confidence: 99%

“…Fourteen studies were performed in European populations, [5][6][7][9][10][11][12]14,[17][18][19][20][21][22] two in Asian populations, 15,16 (with one reporting a target INR 2.0-3.0 15 ) and two in North American populations. 8,13 Proietti et al 11 studied a mixed indication clinical trial cohort including patients from Europe, Asia and Australasia.…”

Section: Searches Identified 166 Citations After Removal Of Duplicatmentioning

confidence: 99%

Use of the SAMe-TT2R2 score to predict anticoagulation control in atrial fibrillation and venous thromboembolism patients receiving vitamin K antagonists: A review

2018

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Identifying patients who are likely to achieve and maintain a therapeutic international normalized ratio when prescribed a vitamin K antagonist for stroke prevention in atrial fibrillation (AF) and venous thromboembolism (VTE) is challenging. The SAMe-TTR score was developed on the basis of common clinical factors that can highlight patients who may be unable to achieve and maintain good anticoagulation control and for whom a "trial of warfarin" would be inadvisable. This review summarizes the main published prospective and retrospective studies that have validated the SAMe-TTR score in patients with AF and VTE treated with a vitamin K antagonist and how the SAMe-TTR score could aid clinical decision making; 19 studies were included. Taken together, validation studies suggest that the SAMe-TTR score is able to predict good or poor anticoagulation control in patients with AF and VTE, although data on patients with VTE are limited (3 studies). The available evidence suggests that the SAMe-TTR score may be a useful tool to aid clinical decision making for oral anticoagulants in patients with AF and VTE.

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“…Практически важно, что снижение когни-тивных функций отражается на приверженно-сти больных терапии, в т. ч. из-за объективно-го снижения памяти при желании соблюдения врачебных рекомендаций, что подтверждается результатами исследований [37][38], показав-ших связь снижения когнитивных функций с более низкими значениями TTR.…”

Section: Discussionunclassified