Assessment of the potential therapeutic effects of omeprazole in Schistosoma mansoni infected mice

Ellakany, Asmaa R.; Elgendy, Dina I.; Alshenawy, Hanan AlSaeid; Ghaffar, Amira E. Abdel

doi:10.1007/s00436-019-06465-w

Cited by 3 publications

(1 citation statement)

References 47 publications

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“…These properties are reported against different infectious agents: antibacterial activity, against Pseudomonas aeruginosa (Sadiq et al 2020), Mycobacterium tuberculosis (Mdanda et al 2017), Ureaplasma urealyticum (Nagata et al 1995), Enterococcus faecalis (Jonkers et al 1996), and Staphylococcus aureus (Jonkers et al 1996;Vidaillac et al 2007); antifungal, against Candida albicans (Biswas et al 2001;Monk et al 1995), Candida spp. (Siavoshi et al 2012), and Saccharomyces cerevisiae (Monk et al 1995 (Riel et al 2002;Skinner-Adams et al 1997), Schistosoma mansoni (Almeida et al 2015;Ellakany et al 2019), Giardia lamblia (Hernández-Ochoa et al 2017), and Tritrichomonas foetus (Sutak et al 2004;Kather et al 2007); antiviral, against SARS-CoV-2 (COVID-19) (Aguila and Cua 2020;Homolak and Kodvani 2020) and rhinovirus (Sasaki et al 2005). In Table 1, we present a summary of the characteristics of PPIs and some of their anti-infective activities.…”

Section: Commentarymentioning

confidence: 99%

Anti-infective properties of proton pump inhibitors: perspectives

et al. 2021

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Infectious diseases are among the main causes of morbidity and mortality today. In facing this crisis, the development of new drug options and combat strategies is necessary. In this sense, drug repositioning or drug redirection has emerged for the faster identification of effective drugs. In this "Commentary," the anti-infective properties of the class of proton pump inhibitors (PPIs) are emphasized. Studies report activities against bacterial, fungal, parasitic, and viral agents. In addition, we have provided in a table a summary of the specific characteristics of PPIs and some of their anti-infective activities.

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