Assessment of the prebiotic potential of globe artichoke by-product through in vitro fermentation by human faecal microbiota

Holgado, Francisca; Campos-Monfort, Gema; Heras, Cristina de las; Rupérez, Pilar

doi:10.1016/j.bcdf.2022.100328

Cited by 4 publications

(2 citation statements)

References 51 publications

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“…The overall content of polyphenols in vegetables ranges from 4 to 185 mg/100 g of fresh weight, with flavonoids, anthocyanins, phenolic acids, tannins, catechins, and quercetin being the most prominent [ 114 , 130 ]. In vitro studies have shown that artichokes exhibit potential prebiotic effects [ 131 , 132 ]. A medium containing artichoke extract led to an increase in beneficial lactic acid bacteria and Bifidobacterium compared to that observed with inulin and sucrose, directly translating to higher levels of short-chain fatty acids (SCFA).…”

Section: Prebioticsmentioning

confidence: 99%

Polyphenols Influence the Development of Endometrial Cancer by Modulating the Gut Microbiota

Baranowska-Wójcik,

Winiarska-Mieczan,

Olcha

et al. 2024

Nutrients

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Dysbiosis of the microbiota in the gastrointestinal tract can induce the development of gynaecological tumours, particularly in postmenopausal women, by causing DNA damage and alterations in metabolite metabolism. Dysbiosis also complicates cancer treatment by influencing the body’s immune response and disrupting the sensitivity to chemotherapy drugs. Therefore, it is crucial to maintain homeostasis in the gut microbiota through the effective use of food components that affect its structure. Recent studies have shown that polyphenols, which are likely to be the most important secondary metabolites produced by plants, exhibit prebiotic properties. They affect the structure of the gut microbiota and the synthesis of metabolites. In this review, we summarise the current state of knowledge, focusing on the impact of polyphenols on the development of gynaecological tumours, particularly endometrial cancer, and emphasising that polyphenol consumption leads to beneficial modifications in the structure of the gut microbiota.

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Section: Prebioticsmentioning

confidence: 99%

Polyphenols Influence the Development of Endometrial Cancer by Modulating the Gut Microbiota

Baranowska-Wójcik,

Winiarska-Mieczan,

Olcha

et al. 2024

Nutrients

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“…(3). Consuming artichokes has been shown to have several health benefits, including protecting the kidney (4), reducing blood fat and blood sugar levels (5), improving gastrointestinal digestive function and preventing arteriosclerosis (6) and so on. However, with the increase in artichoke production, there is also an increase in waste, which is rich in dietary fiber (DF).…”

Section: Introductionmentioning

confidence: 99%

Physicochemical properties of superfine grinding-microwave modified artichoke soluble dietary fiber and their alleviation of alcoholic fatty liver in mice

Wang,

He,

Zhang

et al. 2023

Front. Nutr.

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The effects of superfine grinding (SG) and microwave treatment (MT) on the structure and physicochemical properties of artichoke soluble dietary fiber (ASDF) and its protective effects on mice with alcoholic fatty liver (AFL) were studied. We compared the changes in structural characteristics and physicochemical properties of ASDF, SG-ASDF (ASDF treated by SG), MT-ASDF (ASDF treated by MT), and CM-ASDF (ASDF treated by SG and MT). Moreover, we evaluated the effects of the obtained ASDF on the growth characteristics, blood lipid levels, and liver of mice with AFL. Our results of the study showed that CM-ASDF had a more concentrated and uniform particle size, a higher extraction rate of ASDF and significantly improved water-holding capacity (WHC), oil-holding capacity (OHC) and water swelling capacity (WSC) of ASDF (p < 0.05). After the ASDF intervention, mice with AFL exhibited a significant improvement in body lipid levels and reduce liver inflammation. Specifically, aspartate aminotransferase (AST), alanine aminotransferase (ALT), malonaldehyde (MDA), Tumor necrosis factor-α (TNF-α) and Interleukin-6 (IL-6) were significantly decreased, while superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) were significantly increased (p < 0.05). And the hematoxylin–eosin (HE) staining results showed significant improvement of hepatic steatosis in mice with AFL. In summary, our study found that both SG and MT could improve the structure and physicochemical properties of ASDF, with CM-ASDF being the most effective. Additionally, CM-ASDF was selected to continue the investigation and demonstrated an excellent protective effect on mice with AFL, with the high dose group (H-ASDF) showing the greatest benefit. These findings provided some new insights for future comprehensive utilization of ASDF and drug development for the treatment of AFL.

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How prebiotics have been produced from agro-industrial waste: An overview of the enzymatic technologies applied and the models used to validate their health claims

Gonçalves

González

Roupar

et al. 2023

Trends in Food Science & Technology

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Assessment of the prebiotic potential of globe artichoke by-product through in vitro fermentation by human faecal microbiota

Cited by 4 publications

References 51 publications

Polyphenols Influence the Development of Endometrial Cancer by Modulating the Gut Microbiota

Polyphenols Influence the Development of Endometrial Cancer by Modulating the Gut Microbiota

Physicochemical properties of superfine grinding-microwave modified artichoke soluble dietary fiber and their alleviation of alcoholic fatty liver in mice

How prebiotics have been produced from agro-industrial waste: An overview of the enzymatic technologies applied and the models used to validate their health claims

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