Assessment of the Quality of Life of Oncological Patients Following Hysterovariectomy Associated with Thrombotic Complications

Abstract

Oncological treatment for post-operative patients is aimed to improve their symptomatic course and life prognosis. However, the subjection of a woman following radical intervention in her reproductive system has a devastating effect on the quality of life in this cohort of patients. Quality of life is one of the modern criteria for assessing the effectiveness of health care. The main tool for measuring quality of life is the standardized questionnaires produced by psychometric methods. European Organization for Research and Treatment of Cancer Quality of Life Questionnaire was used to assess the quality of life of women with cancer with post-operative thrombotic complications. The purpose of the study was to assess the indicators dynamics of the quality of life in oncological patients before and after a hysterovariectomy associated with thrombotic complications. Materials and methods. In accordance with the purpose of the study, a comprehensive examination of 34 women with oncological diseases of the uterus and appendages with postoperative deep vein thrombosis, who were in hospital, was done. The average age of patients was 51.4 士 3.5. All patients underwent hysterovariectomy. The control group consisted of 30 healthy women. The set of diagnostic and therapeutic measures included a thorough clinical examination with anamnesis, features of menstrual and reproductive functions, transvaginal ultrasound scanning, hysteroscopy and histological examination of macrodrugs removed during surgery. The groups were compared by age, volume of surgery and comorbidities. Results and discussion. Analysis of the initial results of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire in oncological patients showed a low statistically significant score in all its scales compared to practically healthy women (p <0.05). In the group of patients with post-operative thrombotic complications, after a hysterovariectomy, there was an evident decrease by 46.5% in physical activity compared to the initial data (p <0.05). In the context of therapy, there has been a decrease in social contacts and in the level of communication due to physical and emotional limitations (p <0.05). The decline in quality of life was associated with an increase in sexual dysfunction in 100% of cases. Conclusion. The assessment of indicators of quality of life in patients with malignant neoplasia of the gynaecological sphere must be monitored before and after rapid treatment to determine the necessary social-medical algorithm of actions to adapt such patients during the rehabilitation period