Assessment of the relationship between coronary artery ectasia and erectile function score

Abstract

The relation between coronary artery ectasia (CAE) and erectile dysfunction (ED) has not been studied so far. Hence, we decided to investigate the erectile function score in patients with CAE. We investigated the international index of erectile function (IIEF)-5 score in 34 men with CAE, 38 men with coronary artery disease (CAD), and 30 male controls with normal coronary arteries whose mean ages were 53.2 ± 5.6, 51.4 ± 7.8, and 49.6 ± 8.6 years, respectively. Erectile function was evaluated by the five-item version of the IIEF-5. Each question is scored from 0 to 5. CAE was defined as being without any stenotic lesions with a visual assessment of the coronary arteries showing a luminal dilatation 1.5-fold or more of the adjacent normal coronary segments. IIEF-5 scores in CAE group were found statistically significantly lower than the control group (Po0.001). There were no statistically significant differences in IIEF-5 scores between CAE and CAD groups (P ¼ 0.13). We have shown for the first time that patients with CAE have lower IIEF-5 scores compared with controls with normal coronary angiograms. Many studies reported that endothelial dysfunction in patients with CAE was more dominant than those with CAD. This study suggests that ED and CAE may be different manifestations of a common underlying vascular pathology and vasculogenic ED is frequently seen in CAE at least as much as in CAD.

Association between microvascular angina and erectile dsyfunction

“…In one study by Akcay et al, 24 it was found that IIEF scores were significantly lower in the group with coronary artery ectasia (CAE) and CAD than in control groups with normal coronary arteries. This study suggests that ED and CAE may be different manifestations of a common underlying vascular pathology and ED is frequently seen in CAE at least as much as in CAD.…”

“…Each question was scored from 1-5 with a maximum score of 25 denoting healthy subjects. ED was classified into five severity levels, ranging from none (22)(23)(24)(25) to severe (5-7). 6 Statistical analysis Continuous variables were given as mean ± s.d.…”

The Investigation of Relationship between Coronary Artery Ectasia, Benign Prostatic Enlargement, and Lower Urinary Tract Symptoms

“…18 Specifically, recent attention has been focused on arterial atherosclerosis as one of the important risk factors BPE, benign prostatic enlargement; IPSS, International Prostate Symptom Score; LUTS, lower urinary tract symptoms; PMR, postmictional residual urine volume; PV, prostate volume; Qmax, maximum mean peak urinary flow rate; other abbreviations as in Table 1. Variables were given as mean AE standard deviation.…”

Coronary artery ectasia as a culprit for acute myocardial infarction: review of pathophysiology and management

“…This was thought to be related to coronary endothelial dysfunction, assessed by plasma asymmetric dimethyl arginine (ADMA) levels and endothelium-dependent flow-mediated dilatation (FMD), having excluded the inflammatory response as a potential contributor (31). Ackay et al (32) found a direct relationship between CAE and erectile dysfunction suggesting that endothelial dysfunction in CAE may manifest in two different forms, thus adding to the already existing pathophysiological confusion.…”