The aim of the study is to select rational axle loads of the rolling stock and establish the conditions for their circulation on the railways of the Republic of Uzbekistan. In this work, research has been carried out to assess the indicators of the stress-strain state of rail track elements from the action of the rolling stock with various axial loads. The dynamic loads from the rolling stock wheel on the rail, tensile stresses at the edges of the rail foot, in wooden sleepers (rubber under-rail pads on reinforced concrete) under the linings, in the ballast under the sleeper, as well as stresses at the main area of the roadbed, were determined. The obtained results of studies on the determination and assessment of the loading of the elements of the permanent way and sub-grade bed under the condition of not exceeding their standard values made it possible to establish the permissible speeds of movement of freight wagons with increased axle loads of 25 and 27 tf on the railways of the Republic of Uzbekistan, depending on the design of the track and the thickness of the ballast layer, which will increase the running and carrying capacity of the most loaded sections of the railway network, reduce operating costs, increase the volume of freight traffic by rail, which will create conditions for the further development of national rail transport in the implementation of export and transit potential.