Assessment of the use of hypolipidemic agents (HAs), mainly statins, in elderly subjects aged 80 years and more in Burgundy: Analysis of 13,211 patients

Manckoundia, Patrick; Lorenzini, Mathieu; Disson-Dautriche, Anne; Petit, Jean‐Michel; Lorcerie, B.; Debost, Emmanuel; Menu, Didier; Pfitzenmeyer, P.

doi:10.1016/j.archger.2011.06.025

Cited by 4 publications

(3 citation statements)

References 36 publications

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“…Indeed, in the FG, a plasma electrolyte test was done in less than half of the patients during the month of the study or the 2 months preceding the study. Only a half of the The mean number of drugs in this study (6.8) is similar to that in another study conducted in 2012 in the same cohort, 29 but is less than that in other geriatric studies. 30 However, this is an ambulatory population and the polypharmacy rate is expected to be lower than in hospitalized patients or nursing home residents.…”

Section: Discussionsupporting

confidence: 79%

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Potentially inappropriate use of furosemide in a very elderly population: An observational study

Rodriguez-Cillero

d’Athis

et al. 2017

Int J Clin Pract

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Section: Discussionsupporting

confidence: 79%

“…The mean number of drugs in this study (6.8) is similar to that in another study conducted in 2012 in the same cohort, but is less than that in other geriatric studies . However, this is an ambulatory population and the polypharmacy rate is expected to be lower than in hospitalized patients or nursing home residents .…”

Section: Discussionsupporting

confidence: 72%

Potentially inappropriate use of furosemide in a very elderly population: An observational study

Rodriguez-Cillero

d’Athis

et al. 2017

Int J Clin Pract

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“…With regard to different statin use among the robust, pre-frail, and frail subgroups, it may be resulted from the fact that aging, frailty, and aggravated polypharmacy as age advances affect age-specific medication use pattern. [36,37] …”

Section: Discussionmentioning

confidence: 99%

Plasma zinc alpha2-glycoprotein levels correlate positively with frailty severity in female elders

Lee

Chang²,

Liu

et al. 2016

Medicine

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Frailty is a geriatric syndrome associated with adiposity. Zinc alpha2-glycoprotein (ZAG), a novel adipokine, is a modulator of body fat mass and positively correlates with age. This observational study aims to investigate the relationship between plasma ZAG levels and frailty in the elderly.We enrolled 189 elder participants from a hospital-based comprehensive geriatric assessment program in Taiwan from January 2007 to June 2008. The demographic data, body weight, body mass index, appendicular skeletal muscle mass index (ASMI), body fat mass percentage, metabolic and inflammatory parameters including plasma tumor-necrosis factor alpha, C-reactive protein and ZAG levels, were assessed. The frailty score was assessed by Fried Frailty Index.The mean age of all participants (91 [48.1%] men and 98 [51.9%] women) was 77.19 ± 6.12 years. Judged by the FFI score, 46 (24.34%) elders were robust, 106 (56.08%) were pre-frail, and 37 (19.58%) were frail. Older men showed greater ASMI and lower fat mass percentage in comparison to older women (P < 0.0001). The log-transformed mean plasma ZAG (μg/mL) level of overall was 1.82 ± 0.11, and it was higher in men than in women (1.85 ± 0.12 vs 1.79 ± 0.1, P = 0.0006). Plasma ZAG levels were different among the robust, pre-frail and frail subgroups (1.78 ± 0.09, 1.83 ± 0.12, 1.83 ± 1.10, respectively, P = 0.028), and the differences were more significant in woman elders (P = 0.005). Further multiple linear regression analysis showed plasma ZAG levels positively correlated with frailty severity in women (P for trend = 0.0435).Plasma ZAG levels positively correlated with frailty severity in woman elders. The difference between sexes suggests certain sex-specific mechanisms may exist to affect the association between plasma ZAG levels and frailty.

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Tratamiento de los factores de riesgo vascular en el paciente mayor de 80 años

Gómez‐Huelgas

Martínez‐Sellés

Formiga³

et al. 2014

Medicina Clínica

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Assessment of the use of hypolipidemic agents (HAs), mainly statins, in elderly subjects aged 80 years and more in Burgundy: Analysis of 13,211 patients

Cited by 4 publications

References 36 publications

Potentially inappropriate use of furosemide in a very elderly population: An observational study

Potentially inappropriate use of furosemide in a very elderly population: An observational study

Plasma zinc alpha2-glycoprotein levels correlate positively with frailty severity in female elders

Tratamiento de los factores de riesgo vascular en el paciente mayor de 80 años

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