Assessment of Total Protein, Albumin, Triglyceride and Total Cholesterol Among Sudanese Patients With Tuberculosis in Khartoum State.

Abstract

Total proteins, albumin, cholesterol, triglyceride and tuberculosis. Background: Tuberculosis or TB is a common and often deadly infectious disease caused by various strains of mycobacterium; usually Mycobacterium tuberculosis in humans. Objectives: The aim of this study to evaluate the level of serum albumin, total proteins, cholesterol and triglyceride among Sudanese patients with Tuberculosis. Methods: Cross sectional study was conducted during the period from March to May 2017, eighty samples from known patients with TB as case and forty samples from healthy person as control. The level of total proteins, albumin, cholesterol and TG was measured using Mindray BS-120; Data were collected using structural questionnaire. Data analysis was carried out by means of statistical package for social science (SPSS version 16). Results: The mean levels of total proteins, albumin, cholesterol and triglyceride showed significant decreased in tuberculosis patients when compared with healthy individuals with (P. value = 0.000, 0.000, 0.015 and 0.000) respectively. There were insignificant different in the levels of total proteins, albumin, cholesterol and TG in tuberculosis patients according to gender. The result of this study showed that, there was significantly decreased in BMI in patients with tuberculoses compared to control group (p-value =0.000). There were negative correlation between the levels of serum total proteins, albumin, total cholesterol , triglyceride and ages.(r=-0.356, p, value=0.001) (r=-0.273,p, value=0.014)(r=-0.296,p , value=0.008)(r=-0.223, p , value=0.047) respectively. Conclusion: The levels of total proteins, albumin, cholesterol and triglyceride were significantly decreased in Tuberculosis patients.