Assessment of toxic metals in groundwater and saliva in an arsenic affected area of West Bengal, India: A pilot scale study

Bhowmick, Subhamoy; Kundu, Amit; Adhikari, Jishnu; Chatterjee, D.; Iglesías, Mònica; Nriagu, Jerome O.; Mazumder, D. N. Guha; Shomar, Basem; Chatterjee, Debashis

doi:10.1016/j.envres.2015.07.005

Cited by 27 publications

(11 citation statements)

References 55 publications

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“… 3 , 50 , 51 Overall, metals can be said to be the key factors impairing the river and may have serious human health implications. 52 Strong correlations of Pb, As and Cd, as shown by their correlation matrix and clustering suggests that these metals may be coming from the same input sources. A strong correlation between As and Cd has also been reported.…”

Section: Discussionmentioning

confidence: 98%

Concentrations and Human Health Risk of Heavy Metals in Rivers in Southwest Nigeria

Adesiyan

Bisi-Johnson

Aladesanmi

et al. 2018

Journal of Health and Pollution

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Background.Rivers are the most vital freshwater resources in the world. In Southwest Nigeria, anthropogenic activity stresses the quantity and quality of water resources.Methods.The present study examined the concentrations and human health risk of five heavy metals (manganese (Mn), arsenic (As), chromium (Cr), cadmium (Cd), and lead (Pb)) in selected rivers in Southwest Nigeria. The determination of heavy metals was carried out by atomic absorption spectrophotometry after digestion with a di-acid mixture 9:4 (v/v) (nitric acid: perchloric acid).Results.All rivers had higher concentrations of the five heavy metals in the dry season except for As in Dandaru (0.012 mg/L) and Asejire (0.016 mg/L). Manganese was observed to have the highest mean concentration among all the five metals in both the rainy and dry seasons across the sampled rivers. Generally, the annual mean concentration of metals followed the order: Mn>Cr>Cd>Pb>As in all the selected rivers.Discussion.The human health risk assessment showed that the hazard index and hazard quotient for ingestion of water for Cd and As in all the sampled rivers were higher than the acceptable limit of 1.0, indicating carcinogenic risk (CR) via direct ingestion of water. The CR via ingestion for As in all of the sampled rivers was above the remedial goal target of 1×10−6. The recorded values for chronic daily intake (CDI) were higher for Cr and Mn in all four sampled rivers.Conclusions.The results of the present study showed that As is a driver for carcinogenic risk through ingestion in all of the sampled rivers compared to other metals.Competing Interests.The authors declare no competing financial interests

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Section: Discussionmentioning

confidence: 98%

Concentrations and Human Health Risk of Heavy Metals in Rivers in Southwest Nigeria

Adesiyan

Bisi-Johnson

Aladesanmi

et al. 2018

Journal of Health and Pollution

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“…Moreover, in forensic medicine, saliva is also useful for screening samples containing species-specific DNA profiles for unknown animal identification [43]. The screening of heavy metal poisoning and other toxic substances in saliva samples is practicable, especially when the blood is not available to obtain due to different reasons, mostly in small children [44,45]. Furthermore, the salivary biomarkers provide vital information regarding the level of stress, even in critically ill pediatric patients [46].…”

Section: Saliva: Composition and Diagnostic Importancementioning

confidence: 99%

Salivary Redox Biomarkers in Selected Neurodegenerative Diseases

Maciejczyk

Gerreth

2020

JCM

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Neurodegenerative diseases (NDDs), such as Alzheimer’s disease, Parkinson’s disease, and Huntington’s disease, are disorders, which cause irreversible and progressive deterioration of the central nervous system. The pathophysiology of NDDs is still not fully explained; nevertheless, oxidative stress is considered as a critical mediator of cerebral degeneration, brain inflammation, as well as neuronal apoptosis. Therefore, it is not surprising that redox biomarkers are increasingly used in the diagnosis of neurodegenerative diseases. As saliva is a very easy to obtain bioliquid, it seems promising to use this biomaterial in the diagnosis of NDDs. Saliva collection is easy, cheap, stress-free, and non-infectious, and it does not require the help of a specialised medical personnel. Additionally, the concentrations of many salivary redox biomarkers correlate with their content in blood serum as well as the degree of disease progression, which makes them non-invasive indicators of NDDs. This paper reviews the latest knowledge concerning the use of salivary redox biomarkers in the diagnosis and prognosis of selected neurodegenerative diseases.

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“…Whereas, the mean concentrations of Cd, Cr, and As were ~ times higher than the respective WHO prescribed values. These high concentrations of hazardous metals (As, Cd, Cr, and Pb) recorded in water samples may have serious human health implications (Bhowmick et al, 2015). The present values of the examined metals were higher than the values reported by Ahmed et al (2012b) in and around DEPZ.…”

Section: Metal Concentrations In Ground and Surface Watermentioning

confidence: 99%

Industrial metal pollution in water and probabilistic assessment of human health risk

Saha

Rahman

Ahmed

et al. 2017

Journal of Environmental Management

389

129

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Concentration of eight heavy metals in surface and groundwater around Dhaka Export Processing Zone (DEPZ) industrial area were investigated, and the health risk posed to local children and adult residents via ingestion and dermal contact was evaluated using deterministic and probabilistic approaches. Metal concentrations (except Cu, Mn, Ni, and Zn) in Bangshi River water were above the drinking water quality guidelines, while in groundwater were less than the recommended limits. Concentration of metals in surface water decreased as a function of distance. Estimations of non-carcinogenic health risk for surface water revealed that mean hazard index (HI) values of As, Cr, Cu, and Pb for combined pathways (i.e., ingestion and dermal contact) were >1.0 for both age groups. The estimated risk mainly came from the ingestion pathway. However, the HI values for all the examined metals in groundwater were <1.0, indicating no possible human health hazard. Deterministically estimated total cancer risk (TCR) via Bangshi River water exceeded the acceptable limit of 1 × 10 for adult and children. Although, probabilistically estimated 95th percentile values of TCR exceeded the benchmark, mean TCR values were less than 1 × 10. Simulated results showed that 20.13% and 5.43% values of TCR for surface water were >1 × 10 for adult and children, respectively. Deterministic and probabilistic estimations of cancer risk through exposure to groundwater were well below the safety limit. Overall, the population exposed to Bangshi River water remained at carcinogenic and non-carcinogenic health threat and the risk was higher for adults. Sensitivity analysis identified exposure duration (ED) and ingestion rate (IR) of water as the most relevant variables affecting the probabilistic risk estimation model outcome.

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Assessment of toxic metals in groundwater and saliva in an arsenic affected area of West Bengal, India: A pilot scale study

Cited by 27 publications

References 55 publications

Concentrations and Human Health Risk of Heavy Metals in Rivers in Southwest Nigeria

Concentrations and Human Health Risk of Heavy Metals in Rivers in Southwest Nigeria

Salivary Redox Biomarkers in Selected Neurodegenerative Diseases

Industrial metal pollution in water and probabilistic assessment of human health risk

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