“…For example, a large number of fMRI studies have revealed that the anxiety levels of individuals with anxiety disorder were associated with the function of PFC regions such as the OFC, the medial PFC, the lateral PFC and the anterior cingulate cortex (Brühl, Delsignore, Komossa, & Weidt, a; Ding et al, ; Etkin & Wager, ; Qiu et al, ; Zhang et al, ). The role of PFC function in predicting anxiety has also been reported in subclinical or healthy populations (Kim et al, ; Tian et al, ; Xue, Lee, & Guo, ). Furthermore, the structural variances of the PFC regions (e.g., the OFC, the medial PFC, the lateral PFC and the anterior cingulate cortex) are found to be linked with anxious symptoms among both clinical and healthy samples (Blackmon et al, ; Brühl et al, b; Ducharme et al, ; Shang et al, ; Spampinato, Wood, De Simone, & Grafman, ; Syal et al, ; Talati et al, ).…”