Purpose To investigate which pre-and postoperative radiographic parameters are significantly correlated with the immediate postoperative coronal balance (CB) in Lenke 5C AIS patients, and to identify any radiographic parameter that is correlated with the ultimate CB at a minimum follow-up of 2 years. Methods Forty Lenke 5C AIS patients were recruited in the current study. Preoperative, immediate postoperative, and the latest follow-up radiographs were reviewed measuring various radiographic parameters related to UIV and LIV. The correlations between different parameters and CB were then studied. Results The average follow-up time was 35.2 months. Correlation analysis showed that the following radiographic parameters significantly associated with the immediate postoperative CB in Lenke 5C patients: preoperative CB (r = 0.66, p \ 0.01), preoperative UIV translation (r = 0.61, p \ 0.01), preoperative LIV tilt (r = 0.61, p \ 0.01), postoperative UIV translation (r = 0.51, p \ 0.05), and postoperative LIV tilt (r = 0.50, p \ 0.05). At the last follow-up, only the final UIV tilt was inversely correlated with the ultimate CB (r = -0.58, p \ 0.05). Seven patients presented with coronal imbalance immediately after surgery. However, only one of the seven patients presented with coronal imbalance at the last follow-up, and