Assessment of visceral adiposity index and lipid accumulation product index as markers of chronic kidney disease among diabetic and hypertensive patients at the Bamenda Regional Hospital, Cameroon: a cross-sectional study

Choumessi, Aphrodite Tchewonpi; Foudjo, Brice Ulrich Saha; Navti, Lifoter Kenneth; Tibi, Ateh Sheron; Njeck, Anweck Thecla; Nantia, Edouard Akono

doi:10.11604/pamj.2022.42.228.33499

Cited by 3 publications

(2 citation statements)

References 40 publications

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“…Abstracts of the remaining 1,172 records were searched, and full texts of 140 studies were assessed for eligibility. Finally, 17 studies were included in the review ( 8-10 , 12 , 16-28 ).…”

Section: Resultsmentioning

confidence: 99%

Association between lipid accumulation product index and chronic kidney disease: A systematic review and meta-analysis

Wu,

Cui,

et al. 2024

Exp Ther Med

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Diabetes mellitus and lipid metabolism disorders are increasingly recognized as key contributors to the development of chronic kidney disease (CKD). The lipid accumulation product (LAP) index, a novel marker of lipid accumulation, has potential implications for CKD risk assessment. The present meta-analysis aimed to assess the association between LAP index and CKD, with an emphasis on varying impacts in diabetic and non-diabetic populations. A comprehensive search for relevant publications was performed using PubMed/MEDLINE, Scopus, Cochrane Library, ScienceDirect and Google Scholar databases, and a meta-analysis of 17 studies was performed to investigate the relationship between LAP index and CKD. The random-effects inverse-variance model employing the DerSimonian-Laird estimator for τ² was utilized to calculate pooled odds ratios (ORs). Diagnostic accuracy was assessed using summary receiver operating characteristic (ROC) curves, with calculations of the area under the ROC curve (AUROC), sensitivity, specificity, likelihood ratios and diagnostic OR. The pooled OR for the association between higher quintiles or tertiles of LAP index and CKD was 1.098 (95% CI: 1.043-1.152), with substantial heterogeneity (I²=91.2%) and evidence of publication bias. Subgroup analysis revealed a stronger association in non-diabetic (OR=2.422, 95% CI: 1.802-3.042) compared with diabetic patients (OR=1.018, 95% CI: 0.993-1.043). The diagnostic accuracy of LAP index for CKD was moderate (AUROC= 0.64), with sensitivity and specificity estimates of 0.58 and 0.63, respectively. In conclusion, in the present study, LAP index demonstrated a modest but significant association with CKD, particularly in non-diabetic patients. Despite its moderate diagnostic accuracy, the LAP index could serve as a valuable tool in CKD risk stratification, particularly when integrated with other clinical markers.

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“…Abstracts of the remaining 1,172 records were searched, and full texts of 140 studies were assessed for eligibility. Finally, 17 studies were included in the review ( 8-10 , 12 , 16-28 ).…”

Section: Resultsmentioning

confidence: 99%

Association between lipid accumulation product index and chronic kidney disease: A systematic review and meta-analysis

Wu,

Cui,

et al. 2024

Exp Ther Med

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“…The calculation of LAP is based on two simple measures: WC and fasting plasma triglyceride levels. LAP is used as a marker of serious conditions, such as MetS, insulin resistance, diabetes mellitus, and nonalcoholic fatty liver disease, as well as the risk of stroke, hypertension, renal dysfunction, and cardiovascular pathologies 19 – 25 .…”

Section: Introductionmentioning

confidence: 99%

The predictive capability of several anthropometric indices for identifying the risk of metabolic syndrome and its components among industrial workers

Konstantinova,

Maslakova,

Ogorodnikova

2024

Sci Rep

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Metabolic syndrome (MetS) is closely associated with adverse cardiometabolic outcomes. The objective of this study was to identify practical methods that could enable the effective identification of MetS based on anthropometric indices. The basis of our study involved retrospective database obtained from routine medical prophylactic examinations. This was a cross-sectional study on the health status of male workers employed in hazardous working conditions at industrial enterprises in the Ural region conducted in 2019. A total of 347 male workers employed under hazardous working conditions were investigated. The presence of MetS was established by a healthcare professional in accordance with the guidelines of the International Diabetes Federation (IDF). Simple linear regression was used to evaluate the associations between anthropometric indices and MetS incidence. Logistic regression was used to determine the odds ratios of MetS in relation to increases in anthropometric indices. ROC curves were calculated to compare the ability of each anthropometric index to predict MetS and to determine the diagnostic thresholds of the indicators considered. According to the IDF criteria, 36.3% of the workers had MetS. A direct relationship was found between the individual components of MetS and the anthropometric indices studied. The highest OR was shown by the Body Roundness Index (BRI) of 2.235 (95% CI 1.796–2.781). For different age quartiles, the optimal cut-off values for predicting MetS were as follows: BRI, 4.1–4.4 r.u.; body shape index (ABSI), 0.080–0.083 m11/6 kg−2/3; and lipid accumulation product (LAP), 49.7–70.5 cm mmol/l. The most significant associations with MetS were observed where the values were greater than these cut-off points (Se = 97.4%). The results of this study demonstrated the rapid use of new anthropometric indicators, which have shown good predictive ability and are quite easy to use.

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The Predictive Capability of Some Anthropometric Indices to Identify the Risk of Metabolic Syndrome and Its Components among Industrial Workers

Konstantinova,

Maslakova,

Ogorodnikova

2024

Preprint

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Metabolic syndrome (MetS) is closely associated with adverse cardiometabolic outcomes. The objective of this study is to search for practical methods that would enable effective identification of MetS based on anthropometric indicators. 347 male workers employed in hazardous working conditions were investigated. The presence of MetS was established in according to the guidelines of the International Diabetes Federation (IDF). Simple linear regression was used to determine the relationship between anthropometric indices and MetS components. Logistic regression provided MetS odds ratios (OR) in relation to increases in anthropometric measures. ROC-curves were calculated to compare the ability of each anthropometric index to predict MetS as well as to determine the diagnostic thresholds of the indicators considered. According to the IDF criteria, 36.3% of the workers had MetS. A direct relationship was found between the individual components of MetS and the anthropometric indices studied. The highest OR was shown by the Body Roundness Index (BRI) 2.235, 95% CI: 1.796-2.781. For different age quartiles, the optimal cut-off values predicting MetS were: for BRI, 4.1-4.4 r.u.; for a body shape index (ABSI), 0.080-0.083 m11/6∙kg-2/3; and for the lipid accumulation product (LAP), 49.7-70.5 cm∙mmol/l. The most significant associations with MetS were observed where the values were higher than these cut-off points (Se = 97.4%).

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Assessment of visceral adiposity index and lipid accumulation product index as markers of chronic kidney disease among diabetic and hypertensive patients at the Bamenda Regional Hospital, Cameroon: a cross-sectional study

Cited by 3 publications

References 40 publications

Association between lipid accumulation product index and chronic kidney disease: A systematic review and meta-analysis

Association between lipid accumulation product index and chronic kidney disease: A systematic review and meta-analysis

The predictive capability of several anthropometric indices for identifying the risk of metabolic syndrome and its components among industrial workers

The Predictive Capability of Some Anthropometric Indices to Identify the Risk of Metabolic Syndrome and Its Components among Industrial Workers

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