2010
DOI: 10.1212/wnl.0b013e3181d0ccca
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Assessment: Symptomatic treatment for muscle cramps (an evidence-based review)

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Cited by 112 publications
(65 citation statements)
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“…The same year, practice guidelines for American neurologists on the symptomatic management of muscle cramps concluded that, although likely effective, quinine should be avoided for routine use because of the potential for toxic effects. 3 Quinine does not have Health Canada approval for the treatment of nocturnal leg cramps, yet it is widely used for this indication. In the linked research article, data underlying Garrison and colleagues' analyses show 340-576 new and 3430-4372 refilled quinine prescriptions per month in British Columbia, presumably for nocturnal leg cramps, between November 2006 and October 2007 inclusive.…”
Section: Key Pointsmentioning
confidence: 99%
See 3 more Smart Citations
“…The same year, practice guidelines for American neurologists on the symptomatic management of muscle cramps concluded that, although likely effective, quinine should be avoided for routine use because of the potential for toxic effects. 3 Quinine does not have Health Canada approval for the treatment of nocturnal leg cramps, yet it is widely used for this indication. In the linked research article, data underlying Garrison and colleagues' analyses show 340-576 new and 3430-4372 refilled quinine prescriptions per month in British Columbia, presumably for nocturnal leg cramps, between November 2006 and October 2007 inclusive.…”
Section: Key Pointsmentioning
confidence: 99%
“…9 Trying potentially less toxic pharmacologic agents could be an option as well, although evidence supporting their efficacy is weak. 3 During the trial, patients should be closely monitored and the quinine stopped after four weeks if there is no benefit. 9 If treatment continues, patients should be followed and advised periodically (e.g., every three months) to try stopping the drug to reassess the benefit.…”
Section: Key Pointsmentioning
confidence: 99%
See 2 more Smart Citations
“…Evidence for the efficacy of magnesium is lacking except for pregnancy-associated cramps [4]. Evidence for calcium channel blockers, carisoprodol, or vitamin B12 is limited or absent [5]. Other non-drug treatments for lower limb muscle cramps have limited value only [6].…”
Section: Introductionmentioning
confidence: 99%