Assessments of Antioxidant Content and the Anti-Carcinogenic Effect of Extracts of Solanum Rostratum Dunal in Human Cancer Cells

Abstract

Cancer includes a group of more than 100 different types of diseases characterized by the accelerated and disorderly growth of abnormal cells. Cancer is a major worldwide public health problem. According to the International Agency for Research on Cancer (IARC), cancer increased to 18.1 million new cases and 9.6 million cancer deaths in 2018 (1). Historically, natural products have been used since ancient times and in folklore for treatment of many diseases (2). Traditional medicine is known the sum total of the knowledge, skills, and practices based on the theories and experiences indigenous to different cultures used in the maintenance of health and for the prevention, diagnosis, improvement, and/or treatment of illness (3). Plants have comprised the basis of traditional medicine systems and their use by the peoples of many cultures has been widely documented. The World Health Organization has estimated that approximately 80% of the worldís inhabitants mainly employ traditional medicine for their primary healthcare (4). Currently, the use of medicinal plants to treat and prevent various types of cancer has experienced a breakthrough. Along with the cancer treatment ranging from surgery and radiation to chemotherapy or immunotherapy, millions of people seek additional options such as complementary and alternative medicine. In traditional Mexican folk medicine, Solanum rostratum has been used for years to treat kidney disorders, stomachache, and digestive disorders and with the use of the infusion of the leaves as a purgative. A tea prepared with the plantís flowers is rec

Exploring biodiversity and ethnobotanical significance of Solanum species in Uzbekistan: unveiling the cultural wealth and ethnopharmacological uses

“… Omar et al (2018) reported the isolation and structure elucidation of linalyl-β-glucopyranoside and apigenin-7-O-glucoside. Liu et al (2021b) isolated pyrrole alkaloids from the leaves of S. rostratum and identified three pairs of novel enantiomeric pyrrole alkaloids: (2′ R )-caffeicpyrrole A, (2′ S )-caffeicpyrrole A, (2′ R )-caffeicpyrrole B, (2′ S )-caffeicpyrrole B, (2′ R )-caffeicpyrrole C, and (2′ S )-caffeicpyrrole C. Authors such as Omar et al (2018) and Valadez Vega et al (2019) demonstrated the antioxidant and anti-carcinogenic effects of S. rostratum .…”