Assigning time‐linked exposure status to controls in unmatched case‐control studies: alcohol use and nearly lethal suicide attempts

Kresnow, Marcie-jo; Powell, Kenneth E.; Webb, Kevin; Mercy, James A.; Potter, Lloyd B.; Simon, Tom; Ikeda, Robin M.; Frankowski, Ralph F.

doi:10.1002/sim.684

Cited by 10 publications

(7 citation statements)

References 5 publications

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“…Vinson et al 20 showed in case-control and case-crossover analyses that odds ratios for violence-related injuries are especially high when the injury is associ--ated with alcohol use during the 6 hours prior to injury (OR = 34; 95% CI = 4.7-250); this finding has been reported by others 6,36,44,45 and confirmed by this research. The risk of suicide attempts was especially high in our study, confirming a more limited finding from a frequency analysis of a case-crossover study in a sample of patients from Australia, Canada, Mexico and the United States 46 as well as a study in Texas 47 and a hospital-based case-control study in Mexico City. 48 Previous case-crossover reports 1 have reported higher, but not statistically significant, ORs for mo--tor vehicle accidents, falls and "other injuries".…”

Section: Research Guilherme Borges Et Al Alcohol Use and Injuries Trsupporting

confidence: 89%

Multicentre study of acute alcohol use and non-fatal injuries: data from the WHO collaborative study on alcohol and injuries

Borges

Cherpitel

Orozco

et al. 2006

Bull World Health Organ

120

121

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Objectives To study the risk of non-fatal injury at low levels and moderate levels of alcohol consumption as well as the differences in risk across modes of injury and differences among alcoholics. Methods Data are from patients aged 18 years and older collected in 2001-02 by the WHO collaborative study on alcohol and injuries from 10 emergency departments around the world (n = 4320). We used a case-crossover method to compare the use of alcohol during the 6 hours prior to the injury with the use of alcohol during same day of the week in the previous week. Findings The risk of injury increased with consumption of a single drink (odds ratio (OR) = 3.3; 95% confidence interval = 1.9-5.7), and there was a 10-fold increase for participants who had consumed six or more drinks during the previous 6 hours. Participants who had sustained intentional injuries were at a higher risk than participants who had sustained unintentional injuries. Patients who had no symptoms of alcohol dependence had a higher OR. Conclusion Since low levels of drinking were associated with an increased risk of sustaining a non-fatal injury, and patients who are not dependent on alcohol may be at higher risk of becoming injured, comprehensive strategies for reducing harm should be implemented for all drinkers seen in emergency departments.

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Section: Research Guilherme Borges Et Al Alcohol Use and Injuries Trsupporting

confidence: 89%

Multicentre study of acute alcohol use and non-fatal injuries: data from the WHO collaborative study on alcohol and injuries

Borges

Cherpitel

Orozco

et al. 2006

Bull World Health Organ

120

121

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“…7,29 Although unintentional injury was the most common for both male and female youth, the second most common intent for male youth was violence-related, and for female youth was self-harm. These results support the broader literature on the role of alcohol as a known risk factor for intentional injuries, 18,30,31 and to the unique role that alcohol plays in the injury experiences of male and female youth. [21][22][23] These findings suggest that injury prevention programs should recognize the differences between the effect of alcohol use on injury outcomes in male and female youth.…”

Section: Discussionsupporting

confidence: 85%

An overview of injuries to adolescents and young adults related to substance use: data from Canadian emergency departments

Black

Asbridge

Lea

2009

CJEM

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Objective: Alcohol is a significant risk factor for injury, and is one of the leading causes of death, disability and premature mortality among young Canadians. This paper provides an overview of alcohol-related injury among adolescents and young adults presenting to Canadian emergency departments (EDs). Methods: We reviewed records from the Canadian Hospitals Injury Reporting and Prevention Program database during the 4-year period between 2000 and 2003. We included individuals younger than 25 years who presented to EDs in 11 pediatric and general hospitals with injuries for which alcohol, either alone or in conjunction with drugs, was recorded as a contributing factor. We examined key socio-demographic and injury-related factors associated with alcohol and drugrelated injuries, including intent and disposition. Results: Alcohol was identified as a factor in 2389 injuries during this 4-year period; 408 (17%) of these cases also involved drug use. Approximately 55% of these patients were male and the majority was between 15 and 19 years of age. Unintentional injuries were the most common presentation, self-harm injuries were more common among female patients and violence-related injuries were more common among male patients. Most patients received treatment for their injuries. However, as age increased, outcome differences were observed between sexes. Conclusion: Alcohol-related injuries are increasing among Canadian youth. These findings highlight the importance of obtaining thorough drug and alcohol histories and measurement, when appropriate, for adolescents and young adults presenting to EDs with injuries.

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“…Control‐subjects were randomly assigned a 3‐hour period based on the distribution of attempt‐times for the case‐subjects who attempted on that day of the week. The control‐subjects' drinking status (yes/no) was based on whether they reported drinking during that 3‐hour period (Kresnow et al, 2001).…”

Section: Methods and Datamentioning

confidence: 99%

Alcohol Consumption and Nearly Lethal Suicide Attempts

Powell

Kresnow

Mercy

et al. 2002

Suicide & Life Threat Behav

Self Cite

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We conducted a case-control study of the association between nearly lethal suicide attempts and facets of alcohol consumption; namely, drinking frequency, drinking quantity, binge drinking, alcoholism, drinking within 3 hours of suicide attempt, and age began drinking. Subjects were 13-34 years of age. In bivariable analyses, all measures were associated with nearly lethal suicide attempts. Odds ratios ranged from 2.4 for alcoholism to 7.0 for drinking within 3 hours of attempt. All exposure variables except age began drinking exhibited a J-shaped relationship between alcohol exposure and nearly lethal suicide attempt. After controlling for potential confounders and other measures of alcohol exposure, drinking within 3 hours of attempt remained most strongly (odds ratios > 6) associated. Alcoholism remained significantly associated in most models, but at lower strength.

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Assigning time‐linked exposure status to controls in unmatched case‐control studies: alcohol use and nearly lethal suicide attempts

Cited by 10 publications

References 5 publications

Multicentre study of acute alcohol use and non-fatal injuries: data from the WHO collaborative study on alcohol and injuries

Multicentre study of acute alcohol use and non-fatal injuries: data from the WHO collaborative study on alcohol and injuries

An overview of injuries to adolescents and young adults related to substance use: data from Canadian emergency departments

Alcohol Consumption and Nearly Lethal Suicide Attempts

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