Assignment of the genes for human β-glucuronidase and mitochondrial malate dehydrogenase to the region pter→q22 of chromosome 7

Abstract

In human fibroblast cultures derived from adults, clones of cells with a common chromosome rearrangement have been widely reported. Cells derived from one of these clones have been used in hybridization experiments using mouse cells to localize the genes for β-glucuronidase and mitochondrial malate dehydrogenase on human chromosome 7. The results of this study indicate that the genes for these isozymes are located on the region pter→q22 of human chromosome 7.

Report of the committee on the genetic constitution of chromosomes 7, 8, and 9

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