This study attempts to use bibliometry as a tool for exploration of the passage of development of the science and technology through analysis of the scientific publications from a developing country by taking into account its state of higher education and the unique political, economic and geo-bioenvironmental conditions. It deals with Nepal considering its scientific output during 1966-2016 reflected as publications indexed in the Web of Science Database. Preliminary examination of the publication record for Nepal reveals a number of the following characteristics: i) low volume, negligible growth and lack of distinct trend until 1989; ii) a marked growth followed by stagnation linked to political instability during the next 15 years; and (iii) recovery and accelerated growth thereafter. Research publications during 2004-2013 increased thrice compared to 1994-2003, with expansion and shifts in disciplinary profile expressed in Essential Science Indicators 22 fields. Detailed bibliometric analysis of the 2004-2013 publications (3,011 articles and reviews) from Nepal suggests the citation impact of about the world average, but very high (76%) average international coauthorship. The disciplinary profile is diverse judging from seven most productive fields (clinical medicine, plant & animal science, environment/ecology, geosciences, agricultural sciences, and chemistry) with 4-40% national disciplinary share. Clinical medicine, geosciences and agricultural sciences exhibit relatively high impact. Fields with the smaller share (<3%), such as molecular biology & genetics, economics & business, psychiatry & psychology, materials science, and biology & biochemistry, exhibit citation impact distinctly higher than the world average. Publications from Nepal show the presence of a vast international collaborative network that is dominated by authors affiliated to institutions in the USA,