Associação De Meningite E Pericardite Na Doença Pneumocócica Invasiva: Um Caso Raro

Souza, Tiago Henrique de; Nadal, José Antonio Hersan; Lopes, Celi Espasandin; Nogueira, Roberto José Negrão

doi:10.1590/1984-0462/;2019;37;1;00009

Cited by 3 publications

(2 citation statements)

References 24 publications

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“…The immaturity of the child’s immune system plays an important role in both the development of the infection and the susceptibility to neurological complications. [ 23 ] Neonatal meningitis exhibits severe clinical outcomes. [ 12 ] Our findings revealed a high number of cases in children under 4 years old, with a notable predominance among those under 1 year old.…”

Section: Discussionmentioning

confidence: 99%

Epidemiological and Financial Aspects of Hospitalizations for Bacterial Meningitis in Brazil

Oliva,

Xavier,

Chaves

et al. 2024

Journal of Global Infectious Diseases

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Introduction: Understanding the epidemiology and cost implications of acute bacterial meningitis is crucial for effective health planning, timely treatment implementation, and comprehensive patient support measures, as well as for determining appropriate hospital expenses. Therefore, we conducted an analysis of hospitalization cases for bacterial meningitis in Brazil from January 2008 to December 2019 Methods: This is a descriptive ecological study that utilized the Hospital Information System of Brazil’s National Unified Health System (SIH/SUS) database. The variables included sex, region, age group, hospitalizations, deaths, lethality rate, and hospital service expenses. The data were tabulated to focus specifically on the epidemiological aspect of bacterial meningitis Results: During the study period, there were 20,207 hospitalizations for bacterial meningitis in Brazil. Men accounted for a higher number of cases, with 11,690 (57.67%), while women had a higher lethality rate of 10.64%. The Southeast region had the highest percentage of both hospitalizations (45.78%) and deaths (46.42%). Bacterial meningitis remains an important cause of morbidity and mortality, particularly in children under 5 years of age. Notably, the elderly and the Northeast region showed higher rates of lethality. The total expenditure on hospital services exceeded 43 million in Brazilian real, with the highest expenditure observed in 2019 and the lowest in 2011 Conclusion: A higher prevalence of the disease was observed in males, in children under 1-year-old and in the southeast region. Hospital expenditures were found to be substantial and increasing over time, underscoring the significance of early diagnosis and the promotion of vaccination campaigns.

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Section: Discussionmentioning

confidence: 99%

Epidemiological and Financial Aspects of Hospitalizations for Bacterial Meningitis in Brazil

Oliva,

Xavier,

Chaves

et al. 2024

Journal of Global Infectious Diseases

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“…В литературе приводятся случаи обнаружения бактериемии методом микроскопического исследования в биологических жидкостях, являющихся в норме стерильными, например, ликворе больных при менингитах и энцефалитах или выпотных жидкостях [4][5][6]. В образцах периферической крови возбудители инфекционных заболеваний выявляются значительно реже и представлены либо гемопаразитами (малярия, трипаносомы, бабезии и др.…”

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Intense bacteremia in sepsis in an HIV-infected patient, detected by microscopy of a peripheral blood smear

Базарный

Sosnin

Nasibullina

2023

VIČ-infekc. immunosupr.

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Sepsis remains relevant especially among people with immunodeficiency. The article presents a case of sepsis with a rapid fatal outcome in an immunodeficient patient. The diagnosis of sepsis was promptly confirmed by detecting bacteremia by microscopy of a stained smear of the patient’s peripheral blood. The publication discusses the problems of lifetime diagnosis of sepsis based on the results of a general blood test. The data on the need for a correct assessment of the results of the 5-diff hematological analyzer in patients using light microscopy data, especially when detecting a large content of erythroblasts, are presented.

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A THERAPEUTIC APPROACH TO MENINGOENCEPHALITIS BY Streptococcus pneumoniae IN BRAZIL

Cupertino,

Jorge Júnior,

Colares

et al. 2024

Rev. Contemp.

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Introduction: Acute bacterial meningoencephalitis (ABM) are severe infections caused by microorganisms that are capable of reaching the meninges, as well as the brain. They areconsidered medical emergencies that require early diagnosis and immediate treatment. However, medical professionals have routinely encountered difficulties resulting from the Streptococcus pneumoniae’s antimicrobial resistance in the medical practice, becoming a public health problem in Brazil. The present article has the objective of revising literature and compiling data on S. pneumoniae’s resistance in ABM cases, with the intent of assisting the decision-making process on which therapy should be adopted. Methods: The study was conducted through the revision of literature regarding the treatment of ABM in humans published in the last 20 years, found in the PubMed/Medline, LILACS and SciELO digital databases. The first selection of articles was carried out by analyzing the titles and abstracts. The selected studies were read completely to determine their eligibility. Results and Discussions: The 45 selected articles described varying resistance of S. pneumoniae's to penicillin and ceftriaxone, which can reach approximately 50% to the first drug. The SIREVA Project (2016), developed in Brazil, deserves do to commended for being able to identify the following resistance patterns of the isolated pathogen in ABM cases: (1) 31,% to penicillins (sample of 334 patients), and (2) intermediate and high resistance to ceftriaxone, 6.9% and 5.6% respectively (sample of 320 patients). Despite the infrequent occurrence, present studies document the emergence of resistance mechanisms in pathogen strains to vancomycin. Nevertheless, the studies conducted in Brazil showed that the S. pneumoniae strains were completely sensitive to the previously mentioned drug. Conclusion: The association of ceftriaxone and vancomycin should be considered the best option to treat pneumococcal ABM in Brazil, due to the severity of the condition and the rising resistance of the pathogen to cephalosporins.

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Associação De Meningite E Pericardite Na Doença Pneumocócica Invasiva: Um Caso Raro

Cited by 3 publications

References 24 publications

Epidemiological and Financial Aspects of Hospitalizations for Bacterial Meningitis in Brazil

Epidemiological and Financial Aspects of Hospitalizations for Bacterial Meningitis in Brazil

Intense bacteremia in sepsis in an HIV-infected patient, detected by microscopy of a peripheral blood smear

A THERAPEUTIC APPROACH TO MENINGOENCEPHALITIS BY Streptococcus pneumoniae IN BRAZIL

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