Associação entre o índice de massa corporal e osteoporose em mulheres da região noroeste do Rio Grande do Sul

Mazocco, Letícia; Chagas, Patrícia

doi:10.1016/j.rbr.2016.07.009

Cited by 18 publications

(11 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…This is in accordance with the fact that with aging there is a decrease in bone strength, as damage accumulation in devitalized bone over time decreases bone strength. 29 Our findings in relation to a positive association of BMI and bone strength are in accordance with previous literature in older subjects; 6,11,12 Papakitsou et al found that BMI is inversely associated with levels of collagen I, as a bone degradation marker. 30 These data are also supported by Shen et al who linked BMI to a higher integral, trabecular and cortical BMD and percent cortical volume.…”

Section: Discussionsupporting

confidence: 91%

“…11 However, some studies have challenged that assumption. 6,7 In our study in an Egyptian cohort of 273 subjects, we found that obesity is associated with better bone dimensional structure and strength, as measured by CSI, in subjects aged ≥55 years old, even after adjustment for gender. Older patients had less bone strength than the younger age group.…”

Section: Discussionmentioning

confidence: 50%

“…1,2 The World Health Organization defined obesity as a body mass index (BMI) ≥30 kg/m 2.3 Obesity and osteoporosis are two conditions associated with an increased prevalence in morbidity and mortality. 4,5 Recent studies have shown both possible protective, 6 and harmful 7 associations between obesity and osteoporosis. With a worldwide increase in both obesity and an aging population, it is important to understand the possible associations between osteoporosis and obesity.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

<p>The Relation Between Calcaneus Stiffness Index as a Measure of Bone Density and Body Mass Index in an Egyptian Cohort</p>

Ali

Said

Adly

et al. 2020

JMDH

View full text Add to dashboard Cite

Background: Obesity and osteoporosis are two conditions that are associated with morbidity and mortality; there is contradictory evidence regarding this association. Purpose: The aim of the current study was to explore further the association between obesity and calcaneus stiffness index (CSI), as a measure of bone density, in a communitybased cross-sectional study in an Egyptian population. Methods: A cross-sectional study was conducted among active subjects, aged ≥20 years old, over one year. CSI was measured by Quantitative ultrasound (QUS), in addition; QUS T-score and Z-score of the non-dominant heel scan were recorded. Results: Two hundred and eighty participants were recruited; 7 subjects were excluded because of Z score more than −2, mean age was 61 (± 11.9) years, and mean BMI was 29.7 (±5.6). Female participants were 77.7%, with mean of age 60.3 (± 11.6); and age range 20-82 years. Male participants were 22.3%, with mean of age 63.6 (± 12.7); and age range 30-80 years. Older subjects (>55 years) had significantly lower CSI and worse T-score than the younger subjects (P < 0.001 for both). In the younger age group, BMI was not significantly associated with CSI, even after adjustment for gender (P= 0.52). However, in the older age group, BMI was significantly associated with stiffness index (P= 0.049, O.R.= 1.73), even after adjustment for gender (P= 0.041, O.R.= 1.7). Conclusion: Compared to young subjects, older subjects (≥55 years) had significantly lower bone strength as measured by CSI, and their BMI was significantly positively associated with bone density. In younger people (<55 years), BMI was not associated with bone strength.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionmentioning

confidence: 50%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

<p>The Relation Between Calcaneus Stiffness Index as a Measure of Bone Density and Body Mass Index in an Egyptian Cohort</p>

Ali

Said

Adly

et al. 2020

JMDH

View full text Add to dashboard Cite

show abstract

“…In a cross-sectional study investigating a total of 412 Brazilian postmenopausal women, aged 40 to 75 years with BMD assessed by DXA at the lumbar spine, a higher BMI was associated with reduced osteoporosis risk [26]. A study with 393 post-menopausal Brazilian women reported a lower prevalence of osteopenia and osteoporosis amongst obese women compared to those with eutrophic BMI (DXA-derived BMD assessment) [27]. Another study in São Paulo, with 413 Brazilian women (52.5% <59 years and 47.5% >60 years) showed the BMI to be a positive predictor for DXA-derived BMD at the femoral neck [28].…”

Section: Discussionmentioning

confidence: 99%

Association between 25-Hydroxyvitamin D, Parathyroid Hormone, Vitamin D and Calcium Intake, and Bone Density in Healthy Adult Women: A Cross-Sectional Analysis from the D-SOL Study

et al. 2019

View full text Add to dashboard Cite

There is still limited data on the association between 25-hydroxyvitamin D (25(OH)D), parathyroid hormone (PTH), and bone health in healthy younger adults, particularly in Latin America. This cross-sectional analysis aimed to investigate the associations of 25(OH)D and plasma PTH concentrations with bone parameters, and potential confounders, in women living in a high (England) or low (Brazil) latitude country. Bone was assessed by either peripheral quantitative computed tomography (pQCT) (England) or dual-energy x-ray absorptiometry (DXA) scan (Brazil), serum 25(OH)D concentrations by high performance liquid chromatography tandem mass spectrometry (HPLC-MS) and PTH by the chemiluminescent method. In participants living in England, total volumetric bone mineral density (vBMD) was significantly higher in women <29 years compared to ≥30 years, and total and cortical vBMD values at the 66% site were negatively correlated with weight and body mass index (BMI). In participants living in Brazil, age was positively correlated with bone mineral density (BMD) at the femur and bone mineral content (BMC), and weight, BMI, and body fat were correlated with BMD (lumbar spine and femur) and BMC. PTH concentrations were negatively correlated with 25(OH)D concentrations, and the prevalence of secondary hyperparathyroidism was 28.6% (n = 14) in participants with concentrations <25 nmol/L and 12.2% (n = 41) with concentrations between 25 and 49.9 nmol/L, compared to 6.3% (n = 79) in those with concentrations ≥50 nmol/L. In conclusion, weight and BMI were significantly correlated with bone parameters in both groups and age was significantly correlated with BMD at the femoral neck for women living in Brazil only. Although 25(OH)D concentrations were not correlated to bone parameters at any sites, in either country, PTH concentrations showed a significant correlation with total vBMD at the 66% site for women living in England. Secondary hyperparathyroidism was more common amongst those with deficient and insufficient vitamin D status.

show abstract

“…Of note, in the present study, the RA patients with osteoporosis had a significantly lower median BMI and QUS-estimated body fat than the RA patients without osteoporosis. If this lower BMI is explained by a lower body fat mass, this observation is explainable by the trend reported in the general population of a low BMI being associated with an increased risk of osteoporosis (43,44), which translates into the lack of the protective effect of adiposity against systemic bone loss. If the observed lower BMI of RA patients with osteoporosis was not due to their lower body fat mass, it must be assumed that these patients had a loss of therapeutic control of their disease activity which is expected to decrease BMI through cytokine production.…”

Section: Discussionmentioning

confidence: 99%

A novel quantitative method for estimating bone mineral density using B‑mode ultrasound and radiofrequency signals‑a pilot study on patients with rheumatoid arthritis

et al. 2019

View full text Add to dashboard Cite

The objective of the present study was to evaluate whether an innovative quantitative ultrasound (QUS) technique, Radiofrequency Echographic Multi Spectromety, which combines B-mode ultrasound and radiofrequency signals, is reliable in typical Romanian patients compared to previous results obtained using dual-energy X-ray absorptiometry (DXA). The study prospectively included previously unscreened post-menopausal females with rheumatoid arthritis (RA) and age-matched healthy controls. Bone mineral density (BMD) measurements were performed with an EchoS machine (Echolight ® ), which combines B-mode ultrasound and radiofrequency signals. The study included 106 RA patients, with a median disease duration of 3.2 (0.5–22) years and 119 controls. RA patients had a significantly lower body weight, body mass index (BMI) and basal metabolic rate (BMR) than the controls, while the prevalence of obesity and body fat differed insignificantly. RA patients had a significantly lower spine and hip BMD, higher fracture risk and higher prevalence of osteoporosis. Compared to RA patients without osteoporosis, those with osteoporosis were significantly older and had a longer menopause duration, but they had a significantly lower BMI, body fat, BMR and prevalence of obesity. Among the controls and RA patients, the median spine and hip BMD became significantly higher as the BMI increased from underweight to obesity. In conclusion, osteoporosis is prevalent among RA patients, as a part of a complex transformation of body mass composition, involving BMI and fat mass. The novel QUS scanning technique was able to replicate the results of the established DXA measurement of BMD and is potentially suitable for screening wide populations for osteoporosis.

show abstract

Associação entre o índice de massa corporal e osteoporose em mulheres da região noroeste do Rio Grande do Sul

Cited by 18 publications

References 32 publications

<p>The Relation Between Calcaneus Stiffness Index as a Measure of Bone Density and Body Mass Index in an Egyptian Cohort</p>

<p>The Relation Between Calcaneus Stiffness Index as a Measure of Bone Density and Body Mass Index in an Egyptian Cohort</p>

Association between 25-Hydroxyvitamin D, Parathyroid Hormone, Vitamin D and Calcium Intake, and Bone Density in Healthy Adult Women: A Cross-Sectional Analysis from the D-SOL Study

A novel quantitative method for estimating bone mineral density using B‑mode ultrasound and radiofrequency signals‑a pilot study on patients with rheumatoid arthritis

Contact Info

Product

Resources

About