Association Between Alcohol Consumption and Nocturnal Leg Cramps in Patients Over 60 Years Old: A Case-Control Study

Delacour, Chloé; Chambe, Juliette; Lefèbvre, François; Bodot, Claire; Bigerel, Elodie; Epifani, Laetitia; Granda, Céline; Haller, Dagmar M.; Maisonneuve, Hubert

doi:10.1370/afm.2238

Cited by 9 publications

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“…In order to explore the association between sedentary lifestyle and cramps, we compared (i) the "sedentary" group and the "very active" group, (ii) the "sedentary" group and the "moderately active" group and (iii) the "sedentary" group and the sum of both active groups with Bayesian univariate conditional logistic and hierarchic linear regressions to take into account the matching. Considering the strong association between the global alcoholic beverage consumption and nocturnal leg cramps 15 , we included the consumption of alcoholic beverage in a multivariate model. We then performed a conditional logistic regression to take the matching into account.…”

Section: Discussionmentioning

confidence: 99%

“…According to their DPAS, participants were distributed into three groups: (i) the "sedentary" group for a score between 0 and 10, (ii) the "moderately active" group between 11 and 20 and (iii) the "active to very active" group between 21 and 30. www.nature.com/scientificreports www.nature.com/scientificreports/ In a previous study, we identified an association between NLC and alcohol consumption among patients over 60 years old attending general practices 15 . In this study, we also used the E3N food frequency questionnaire to identify the consumption of alcoholic beverages 30,31 and distributed the participants into groups of consumers and non-consumers of alcoholic beverage (self-reported use in the past year).…”

Section: Data Collectionmentioning

confidence: 94%

“…The STrengthening the Reporting of OBservational studies in Epidemiology (STROBE) statement was used to guide the reporting of the study. Detailed methods are available in a previous paper 15 .…”

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Association between physical activity and Nocturnal Leg Cramps in patients over 60 years old: a case-control study

Delacour

Chambe

Lefèbvre

et al. 2020

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Legs cramps are a frequent disorder, which have a negative impact on quality of life, particularly among patients over 60 years old. Lifestyle factors such as alcohol consumption have been shown to be associated with nocturnal Leg cramps. this study aimed to explore the association between nocturnal leg cramps and a sedentary lifestyle among elderly patients. A case-control study was conducted with a Bayesian approach for sensitivity analysis. Patients over 60 years old consulting their family doctor were recruited in the Alsace region, france. cases were matched with controls free from cramps for age, sex, medical history and medications known to trigger cramps. the level of physical activity was assessed using the Dijon physical Activity Score (DpAS). We performed univariate and multivariate analyses adjusting for alcohol consumption. 272 participants were matched into 136 pairs. 11% of all were sedentary persons. Adjusting for alcohol consumption, we observed an association between nocturnal Leg cramps and a sedentary lifestyle oR = 9.84 (95% credibility interval [1.74; 101.9]; posterior probability 99.68%). Our findings represent an additional argument to promote physical activity to patients over 60 years old. They also highlight the need to develop and evaluate physical activity interventions in the treatment of nocturnal Legs cramps. Nocturnal Leg Cramps (NLC) are painful, involuntary contractions of muscles 1-3. NLC is a specific entity of idiopathic cramps occurring at rest in the lower limb during the night 4-7. NLC are associated with a reduced quality of sleep 6 and reduced physical component scores on the SF36 quality of life questionnaire 8. Among patients over 60 years old the cramp prevalence varies from 46% to 56% 4,9. Nonetheless, patients rarely report NLC to their general practitioners 4,10,11. One of the reasons may be the known lack of both effective and safe treatments 9,11-13. Specific medical conditions and drug treatments have been identified to be associated with muscle cramps 10,14. Recently, we also showed a strong association with the global consumption of alcoholic beverages 15. Still, most cramps are considered idiopathic 16 and their physiological mechanism remains unclear 10,14. Some authors suggest that neuromuscular structures located in muscle, tendons and nerve fibres seem to be involved in the trigger of muscle cramps 4-6. Congruently with this assumption, musculoskeletal conditions associated with sedentary lifestyle 17 as well as work postures 18-20 , prolonged standing 21 and western habit of sitting instead of squatting 22 have been suspected of causing cramps and specifically NLC. We hypothesize that there may be an association between sedentary lifestyle and NLC. To the best of our knowledge, no study confirmed such a link, our aim was therefore to assess the association between a sedentary lifestyle and Nocturnal Leg Cramps in elderly patients. Methods Study design. The study was conducted within 67 general practices of the Strasbourg General Medicine Department pract...

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Section: Data Collectionmentioning

confidence: 94%

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Association between physical activity and Nocturnal Leg Cramps in patients over 60 years old: a case-control study

Delacour

Chambe

Lefèbvre

et al. 2020

Sci Rep

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“…7 Delacour et al find a strong association between alcohol consumption and leg cramps in general practice patients aged over 60 years. 8 They don't find a dose-response effect, but I wonder if the immediacy of leg cramps could be a motivator for some patients for whom the long-term effects of alcohol overuse are not compelling.…”

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In This Issue: Teachable Moments for Patients, Practices, and Systems

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2018

Ann Fam Med

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Sleep After Traumatic Brain Injury

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2022

Sleep and Neuropsychiatric Disorders

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Association Between Alcohol Consumption and Nocturnal Leg Cramps in Patients Over 60 Years Old: A Case-Control Study

Abstract: We identified an association between alcohol consumption and nocturnal leg cramps among patients aged 60 years and older attending general practices. These findings have implications for the prevention of cramps.

Cited by 9 publications

References 42 publications

Association between physical activity and Nocturnal Leg Cramps in patients over 60 years old: a case-control study

Association between physical activity and Nocturnal Leg Cramps in patients over 60 years old: a case-control study

In This Issue: Teachable Moments for Patients, Practices, and Systems

Sleep After Traumatic Brain Injury

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