Association Between Anatomical Variations of the Sinonasal Region and Chronic Rhino-Sinusitis: A Prospective Case Series Study

Abstract

Chronic rhinosinusitis is a chronic inflammation of the nasal and paranasal cavities. However, the main pathophysiology of these chronic conditions is poorly described and seems to be multifactorial.In the present study, we reviewed the computed tomography (CT) scans of patients with chronic rhinosinusitis to identify a probable association between the anatomical variations and chronic inflammation in the sinonasal region.Prospective study of the axial and coronal CT scans of 206 chronic rhinosinusitis patients between September 2010 and January 2012 was performed.The study population involved 100 males (48.5%) and 106 females (51.4%) with a mean age of 39 years. The ostiomeatal complex was reported patent in 43 subjects and was blocked in 36 patients. The nasal septa were significantly deviated in 117 (56.7%) patients. Turbinate hypertrophy was reported in 55 (26.6%) patients. Retention cyst was observed in 56 (27.1%) participants. Concha Bullosa and polyps were reported in 36 (17.47%) and 38 (18.44%) patients, respectively. Maxillary sinus was the most common site of involvement (67 patients).Our investigation revealed that there is a strong association between the presence of anatomical variations and chronic inflammation in the paranasal sinuses.

A CT and DNE study of osteomeatal complex variations and their correlation in chronic rhinosinusitis patients

“…Mamatha et al, Fadda et al and Madani et al correlated well with our study showing maxillary sinus to be the most common sinus involved. 18,20,25 Fadda et al observed in their study, statistical correlation between concha bullosa and maxillary sinusitis, between medial deviation of uncinate process and anterior ethmoid sinusitis, between agger nasi cells and frontal sinusitis and between septal deviation and maxillary sinusitis. 20 These correlations are similar to the ones found in our study.…”

A Comparative Evaluation Between Ct Scan PNS WTH Nasal Endoscopy Findings in Patients of Chronic Rhinosinusitis

“…Their clinical features, endoscopic and CT scan findings were studied in detail as per pretested proforma. 13 showed slight female preponderance of 51.7% and 51.4% respectively.In present study, the most common major factor seen in patients of chronic rhinosinusitis was nasal obstruction seen in 92 (88.46%) cases, followed by nasal discharge/post nasal drip in 84 (80.77%) cases. Least common presenting symptom was hyposmia or anosmia seen in 16 (15.38%) cases.…”

Clinical Study of Septal Deviation and Its Association with Sinusitis

“…While in the study by Venkatachalam et al (2000) the commonest symptoms were nasal obstruction in 87%, nasal discharge in 70% of patients and the other symptoms were post nasal drip in 41% and abnormalities in sensation of smell in 36% of patients [12]. In another study by Nayak et al (1991) nasal discharge was the commonest complaint seen in 78.2%, while nasal blockage and headache was seen in 75.6% of patients [8] In our study patients bilateral maxillary sinusitis was seen in 24 patients (48%), unilateral maxillary sinusitis in 8 patients (16%), bilateral frontal sinusitis in 6 patients (12%), unilateral frontal sinusitis in 4 patients (8%), bilateral anterior ethmoidal sinusitis in 8 patients (16%), unilateral anterior ethmoidal sinusitis in 11 patients (22%), unilateral posterior ethmoidal sinusitis was seen in 9 patients(18%) and bilateral posterior ethmoidal sinusitis was seen in 5 patients ( 10%) and bilateral sphenoidal sinusitis was seen in 2 patients (4%). 3 patients had pansinusitis (6%)…”

“…[6,7] In the present study the incidence of DNS was more in male than female with an approximate ratio of 1.6:1 which is in agreement to a study done by Nayak et al . [8] In a study by Madani et al, there were 68.3% male and 31.7% female with a mean age of 29.13±15.21 years. [9] Ozkurt et al in his study observed that incidence was more in male as compared to female .…”