2018
DOI: 10.1177/0284185118787359
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Association between aortic valvular calcification and characteristics of the aortic valve in patients with bicuspid aortic valve stenosis

Abstract: Background Aortic valve calcification quantification using cardiac computed tomography (CCT) is a reliable marker for aortic stenosis (AS) in patients with bicuspid aortic valve (BAV) disease. Purpose To determine the association of Agatston aortic valve calcium score (AVCS) with morphological and hemodynamic characteristics of BAV and define cut-off AVCS for optimizing the grade of AS in patients with bicuspid AS. Material and Methods This study included 161 BAV patients with AS regardless of aortic regurgita… Show more

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Cited by 11 publications
(3 citation statements)
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“…In a large crossectional study of 852 BAV [35] patients, we found age, arterial hypertension, dyslipidemia, smoking, and the BAV-RN morphotype to be associated with aortic valve calcification. However, CT score was not associated with valve phenotype [38].…”
Section: Valve Calcificationmentioning
confidence: 75%
“…In a large crossectional study of 852 BAV [35] patients, we found age, arterial hypertension, dyslipidemia, smoking, and the BAV-RN morphotype to be associated with aortic valve calcification. However, CT score was not associated with valve phenotype [38].…”
Section: Valve Calcificationmentioning
confidence: 75%
“…The cutoff level was comparable with the previous studies. Choi et al Demonstrated the cut-off value of 1423 AU in women and 2573 AU in men with AUC of 0.8 23 . Similarly, Boulif et al demonstrated mean value of AVCS was 3534 ± 1777 AU 15 , and Ren et al (3497.71 ± 2470.17 AU) 29 .…”
Section: Discussionmentioning
confidence: 99%
“…2,3 The progression of AS in both phenotypes shares a common disease process of inflammation, calcium deposition, and ossification, however, patient charachteristics and evolution have differences that should be evaluated. [4][5][6][7] Previous studies have shown that AS severity progress slowly over time in patients with BAV, but they have included young adults with BAV, most of them without significant aortic valve dysfunction. [8][9][10] But according to recent evidence, it seems possible that when calcification proccess begins, patients with BAV will show a higher rate of progression and of aortic valve intervention requirement.…”
Section: Introductionmentioning
confidence: 99%