Association between atrial fibrillation burden and cognitive function in patients with atrial fibrillation

Tang, Sung‐Chun; Liu, Yen‐Bin; Lin, Lian‐Yu; Huang, Hui‐Chun; Ho, Li‐Ting; Lai, Ling‐Ping; Chen, Wen‐Jone; Ho, Yi-Lwung; Yu, Chih-Chieh

doi:10.1016/j.ijcard.2023.01.007

Cited by 8 publications

(4 citation statements)

References 18 publications

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“…Given the variable efficacy of anti-arrhythmic drugs in maintaining sinus rhythm, studies should also be designed to measure atrial fibrillation burden and examine whether it correlates with cognitive outcomes. Tang et al, have recently identified a potential link between atrial fibrillation burden and cognitive function in a prospective cohort study of 253 patients with established diagnoses of atrial fibrillation [79]. The authors found that patients with higher burdens of atrial fibrillation appeared to have lower Montreal Cognitive Assessment scores.…”

Section: Pharmacological Rhythm Control Therapymentioning

confidence: 99%

The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function

Bodagh

Kotadia

Gharaviri

et al. 2023

JCM

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There is increasing evidence to suggest that atrial fibrillation is associated with a heightened risk of dementia. The mechanism of interaction is unclear. Atrial fibrillation-induced cerebral infarcts, hypoperfusion, systemic inflammation, and anticoagulant therapy-induced cerebral microbleeds, have been proposed to explain the link between these conditions. An understanding of the pathogenesis of atrial fibrillation-associated cognitive decline may enable the development of treatment strategies targeted towards the prevention of dementia in atrial fibrillation patients. The aim of this review is to explore the impact that existing atrial fibrillation treatment strategies may have on cognition and the putative mechanisms linking the two conditions. This review examines how components of the ‘Atrial Fibrillation Better Care pathway’ (stroke risk reduction, rhythm control, rate control, and risk factor management) may influence the trajectory of atrial fibrillation-associated cognitive decline. The requirements for further prospective studies to understand the mechanistic link between atrial fibrillation and dementia and to develop treatment strategies targeted towards the prevention of atrial fibrillation-associated cognitive decline, are highlighted.

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Section: Pharmacological Rhythm Control Therapymentioning

confidence: 99%

The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function

Bodagh

Kotadia

Gharaviri

et al. 2023

JCM

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“…If AF burden can be identified as the main cause of cognitive decline, more focus can be placed on approaches to reduce it. 50 - 52 …”

Section: Introductionmentioning

confidence: 99%

Artificial Intelligence-Based Clinical Decision Support Systems in Cardiovascular Diseases

Bozyel

2024

Anatol J Cardiol

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Despite all the advancements in science, medical knowledge, healthcare, and the healthcare industry, cardiovascular disease (CVD) remains the leading cause of morbidity and mortality worldwide. The main reasons are the inadequacy of preventive health services and delays in diagnosis due to the increasing population, the failure of physicians to apply guide-based treatments, the lack of continuous patient follow-up, and the low compliance of patients with doctors’ recommendations. Artificial intelligence (AI)-based clinical decision support systems (CDSSs) are systems that support complex decision-making processes by using AI techniques such as data analysis, foresight, and optimization. Artificial intelligence-based CDSSs play an important role in patient care by providing more accurate and personalized information to healthcare professionals in risk assessment, diagnosis, treatment optimization, and monitoring and early warning of CVD. These are just some examples, and the use of AI for CVD decision support systems is rapidly evolving. However, for these systems to be fully reliable and effective, they need to be trained with accurate data and carefully evaluated by medical professionals.

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“…The rising incidence of AF worldwide highlights its significant clinical impacts, including increased risks of stroke, heart failure, systemic embolism, and a growing link to cognitive decline and dementia, potentially due to microembolisms, bleeds, non-cortical/cortical infarcts, and chronic hypoperfusion. These factors collectively contribute substantially to morbidity and mortality [4,5]. In Nigeria, for example, the coexistence of AF and heart failure (HF) presents a troubling scenario for cardiovascular health.…”

Section: Introductionmentioning

confidence: 99%

Exploring the Epidemiology of Atrial Fibrillation in Nigeria: A Focus on Atrial Fibrillation in Heart Failure Patients and Its Association With Stroke

Otabor,

Alaka,

Onwuzo

et al. 2024

Cureus

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Atrial fibrillation (AF) represents a significant global public health concern, particularly due to its association with adverse health outcomes such as stroke and heart failure. In Nigeria, where the burden of cardiovascular diseases is rising, understanding the prevalence and impact of AF is crucial for effective healthcare planning and intervention strategies.This review examines the epidemiology of AF in Nigeria, comparing it with global and African data. It explores demographic and regional variations, comorbidity factors, and the impact of AF on the healthcare system, mortality, and quality of life.Notably, the prevalence of AF in Nigeria generally falls just under 5%, but this figure rises to approximately 9% in stroke patients and 11-20% among those with heart failure (HF). Rheumatic heart disease (RHD) is identified as a significant AF risk factor within Africa, affecting around 20% of AF patients -a stark contrast to the 2% in North America. AF's association with higher mortality rates and functional deterioration highlights the urgent need for improved diagnostic and therapeutic approaches, alongside broader public health measures.In conclusion, the review emphasises the significant public health concern AF represents in Nigeria, especially among HF and stroke patients, and stresses the importance of tailored healthcare policies and interventions to mitigate AF's impact and improve patient outcomes.

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Association between atrial fibrillation burden and cognitive function in patients with atrial fibrillation

Cited by 8 publications

References 18 publications

The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function

The Impact of Atrial Fibrillation Treatment Strategies on Cognitive Function

Artificial Intelligence-Based Clinical Decision Support Systems in Cardiovascular Diseases

Exploring the Epidemiology of Atrial Fibrillation in Nigeria: A Focus on Atrial Fibrillation in Heart Failure Patients and Its Association With Stroke

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