Association between Blood Glucose Control and Subjective Cognitive Decline in Korean Patients with Diabetes Aged over 50 Years

Abstract

This study aimed to investigate the association between blood glucose control and subjective cognitive decline in adult patients with diabetes. Using the 2018 data from the community health survey, we included 18,789 patients with diabetes aged ≥50 years who had complete responses recorded. Blood glucose control was the independent variable, and subjective cognitive decline was the dependent variable. Multivariable logistic regression analysis was used to analyze the association between blood glucose control and subjective cognitive decline. Multivariable logistic regression analysis showed that blood glucose control was inversely associated with subjective cognitive decline in patients with diabetes. Patients with uncontrolled blood glucose levels had higher odds of subjective cognitive decline than those with controlled blood glucose levels (odds ratio = 1.22; 95% confidence interval: 1.10, 1.34). Our findings suggest that patients with diabetes may demonstrate subjective cognitive decline if their blood glucose levels are not well-controlled.

Cognitive frailty in older adults with diabetes: prevalence and risk factors

“…The association between HbA1c levels ≥8.5% and cognitive frailty underscores the importance of glycemic control in mitigating the risk of cognitive decline. Diabetic patients over 50 years old with uncontrolled blood glucose levels are at higher risk of cognitive decline then individuals with controlled blood glucose levels (Koh et al 2022). As such, community professionals should aim to educate patients about the relevance and importance of glycaemic control and testing as there is a positive association between HbA1c self-awareness and blood glucose control (Almutairi et al, 2022).…”