Association between calcification in the coronary arteries, aortic arch and carotid arteries: The Rotterdam study

Odink, Arlette E.; Lugt, Aad van der; Hofman, Albert; Hunink, M. G. Myriam; Breteler, Monique M.B.; Krestin, Gabriël P.; Witteman, Jacqueline C. M.

doi:10.1016/j.atherosclerosis.2006.07.007

Cited by 119 publications

(108 citation statements)

References 19 publications

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“…10 Both studies confirmed the association between age and calcifications, an association that was also found in coronary artery studies. 2 The present study found a higher prevalence and volume of calcifications in men, a finding that is in agreement with studies on coronary arteries 16,17 and carotid bifurcations. 17 One study found an independent association between sex and intracranial internal carotid artery calcifications, 11 whereas another study did not find this association.…”

Section: Discussionsupporting

confidence: 93%

“…2 The present study found a higher prevalence and volume of calcifications in men, a finding that is in agreement with studies on coronary arteries 16,17 and carotid bifurcations. 17 One study found an independent association between sex and intracranial internal carotid artery calcifications, 11 whereas another study did not find this association. 10 In the present study, we found that smoking and hypercho- lesterolemia are independently associated with the presence of intracranial calcifications.…”

Section: Discussionsupporting

confidence: 93%

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Intracranial Internal Carotid Artery Calcifications: Association with Vascular Risk Factors and Ischemic Cerebrovascular Disease

Weert¹,

Cakir²,

Rozie³

et al. 2008

AJNR Am J Neuroradiol

103

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BACKGROUND AND PURPOSE:Atherosclerotic calcifications are present not only in the extracranial carotid bifurcation but also in the intracranial part of the internal carotid artery. We assessed the association between intracranial internal carotid artery calcifications and cardiovascular risk factors in patients with ischemic cerebrovascular disease and the association between calcifications and the presence of this disease.

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Section: Discussionsupporting

confidence: 93%

Section: Discussionsupporting

confidence: 93%

Intracranial Internal Carotid Artery Calcifications: Association with Vascular Risk Factors and Ischemic Cerebrovascular Disease

Weert¹,

Cakir²,

Rozie³

et al. 2008

AJNR Am J Neuroradiol

103

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“…There is a strong correlation between amount of coronary and aortic calcification and carotid calcification or IMT. (28)(29)(30)The amount of aortic calcium could be used as a marker of atherosclerosis among younger women with very low prevalence of CAC.…”

Section: Discussionmentioning

confidence: 99%

Incident coronary artery calcium among postmenopausal women

et al. 2008

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Recent studies have shown that individuals with 0 coronary artery calcium (CAC) scores have very low risk of coronary heart disease. In the Healthy Women Study, we evaluated development of new CAC among postmenopausal women (n=272) over a 6 year period, age 62 at the 1 st and 68 at the 3 rd electron beam tomography (EBT) examination. At the 1 st EBT, 155 of 272 (57%) women had 0 CAC. By the 3 rd , 56 (36%) of these women had developed new CAC, including 38 with >5 Agatston units. There was practically no regression from having CAC at with the 1 st EBT to no CAC at the 3 rd EBT. The risk of developing new CAC over 6 years among women with 0 CAC on their 1 st EBT was strongly and significantly related to presence of both aortic calcium and carotid plaque at the time of 1 st EBT. Baseline premenopausal risk factors, age 47, apolipoprotein B, body mass index (BMI) and triglycerides, were significant predictors of incident CAC as were the changes in BMI and low density lipoprotein cholesterol between premenopause and the 1 st post exam, age 53. Risk factors measured premenopause and change in risk factors from premenopause to the 1 st post exam and the extent of subclinical disease in other vascular beds are primary determinants of the risk of developing incident CAC in women over a 6 year period.

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“…6,7 Furthermore, it is feasible that not only plaque severity but also plaque composition vary according to location. 8 Some plaque components, such as intraplaque hemorrhage (IPH), are presumed to enhance vulnerability of the plaque, whereas calcification may promote plaque stability.…”

mentioning

confidence: 99%

Atherosclerotic Plaque in the Left Carotid Artery Is More Vulnerable Than in the Right

Selwaness

Bouwhuijsen

Onkelen

et al. 2014

Stroke

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Background and Purpose-Ischemic stroke is more often diagnosed in the left hemisphere than in the right. It is unknown whether this asymmetrical prevalence relates to differences in carotid atherosclerosis. We compared atherosclerotic plaque prevalence, severity, and composition between left and right carotid arteries. Methods-In a population-based cohort, carotid MRI scanning was performed in 1414 stroke-free participants (≥45 years).Using a multisequence MRI protocol, we assessed the prevalence, stenosis, and thickness of the plaque and its predominant component (ie, lipid core, intraplaque hemorrhage, calcification, or fibrous tissue in each carotid artery

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Association between calcification in the coronary arteries, aortic arch and carotid arteries: The Rotterdam study

Cited by 119 publications

References 19 publications

Intracranial Internal Carotid Artery Calcifications: Association with Vascular Risk Factors and Ischemic Cerebrovascular Disease

Intracranial Internal Carotid Artery Calcifications: Association with Vascular Risk Factors and Ischemic Cerebrovascular Disease

Incident coronary artery calcium among postmenopausal women

Atherosclerotic Plaque in the Left Carotid Artery Is More Vulnerable Than in the Right

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