Association between Chages in Plasma Calcium Concentration and Plasma Tartrate-Resistant Acid Phosphatase Activity in Periparturient Cows.

Sato, Jun; Sato, Ryo; Takagi, Aiko; Goto, Taichi; Okada, Keiji; Yasuda, Jun; Naito, Yoshihisa

doi:10.1292/jvms.65.291

Cited by 4 publications

(5 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The study reported here appears to be the first involving a large number of dairy cattle (n = 104) that permitted a more complete characterization of the change in plasma [Ca] during the 24-h period before and after parturition. It should be noted that our re-sults were consistent with those reported in 5 studies involving small numbers of dairy cows that identified a prepartum decrease in plasma [Ca] below 2.15 mmol/L (Horst et al, 1978;Horst and Jorgensen, 1982;Goff et al, 1989;Sato et al, 2003;Kimura et al, 2006). However, the dairy cows used in those studies were not fed an acidogenic diet in the late dry period and most showed clinical signs of hypocalcemia, and the specific timing of the decrease in plasma [Ca] relative to parturition was not well characterized.…”

Section: Discussionsupporting

confidence: 91%

Plasma calcium concentrations are decreased at least 9 hours before parturition in multiparous Holstein-Friesian cattle in a herd fed an acidogenic diet during late gestation

Megahed¹,

Hiew²,

Badawy³

et al. 2018

Journal of Dairy Science

View full text Add to dashboard Cite

Calcium homeostatic mechanisms are challenged in periparturient multiparous dairy cattle due to the rapid transport of large amounts of calcium into the mammary gland associated with colostrogenesis, resulting in decreased plasma total calcium concentration ([Ca]). An unresolved issue is the timing of the decrease in plasma [Ca] relative to the time of parturition, with the consensus view being that plasma [Ca] does not decrease until after parturition. The objective of this study, therefore, was to characterize the change in plasma [Ca] over time in periparturient dairy cattle. Plasma and mid-stream urine samples were collected daily starting 3 d before calving from 104 periparturient Holstein-Friesian dairy cows in a herd fed an acidogenic total mixed ration during the late dry period. Mixed-models ANOVA and linear and multivariable regression analyses were conducted. Plasma [Ca] decreased in periparturient multiparous cattle (n = 70) but not in primiparous cattle (n = 34). Compared with mean values approximately 72 h before parturition ([Ca] = 2.32 mmol/L), mean plasma [Ca] in multiparous cattle first decreased at 9 h before parturition (2.13 mmol/L) and remained decreased for up to 48 h after parturition, with the lowest mean value (1.87 mmol/L) occurring at 28 h after parturition. Mean 24-h urine Ca excretion was calculated to decrease by 3.5 to 3.8 g in periparturient multiparous cattle. Regression analysis indicated that plasma [Ca] in the 12-h period before and 24-h period after parturition was strongly and negatively associated with age but was also negatively associated with milk production indices. We conclude that plasma [Ca] was decreased at least 9 h before parturition in multiparous dairy cattle fed an acidogenic diet in late gestation, and that calcium homeostasis was disrupted for 2 to 3 d around parturition.

show abstract

Section: Discussionsupporting

confidence: 91%

Plasma calcium concentrations are decreased at least 9 hours before parturition in multiparous Holstein-Friesian cattle in a herd fed an acidogenic diet during late gestation

Megahed¹,

Hiew²,

Badawy³

et al. 2018

Journal of Dairy Science

View full text Add to dashboard Cite

show abstract

“…1970; Liesegang et al . 2000; Sato et al . 2003) reported that bone resorption activity does not increase within the 2 days after parturition.…”

Section: Discussionmentioning

confidence: 99%

Effects of calcium intake and parity on plasma minerals and bone turnover around parturition

Kamiya

Tanaka

et al. 2005

Animal Science Journal

View full text Add to dashboard Cite

Eight pregnant heifers (primiparous cows) and seven pregnant cows in their second, third and forth pregnancies (multiparous cows) were assigned to two groups and fed either a low calcium (Ca) diet (Ca, 0.46%) or a high Ca diet (Ca, 0.86%) ad libitum from 3 weeks before the expected calving date to 3 days after parturition. All cows were examined for a change in dry matter intake (DMI), plasma minerals and bone turnover around parturition. The dietary Ca level did not affect the DMI in both primiparous and multiparous cows. The DMI of primiparous cows was significantly lower than that of multiparous cows ( P < 0.05) in both the low and high dietary Ca groups. The dietary Ca level did not affect the concentrations of plasma Ca, phosphorus, magnesium and parathyroid hormone throughout the experimental period. Plasma phosphorus in primiparous cows was significantly higher ( P < 0.05) than that of multiparous cows around parturition. Plasma Ca and magnesium tended to be higher ( P < 0.10) in primiparous cows. The dietary Ca level did not affect the plasma osteocalcin (OC) level measured as bone formation or the urinary deoxypyridinoline (DPD) excretion measured as bone resorption before parturition in both primiparous and multiparous cows. After parturition, the plasma OC level was lower than it was before parturition in multiparous cows fed a low Ca diet, and in primiparous cows. There were no significant differences in urinary DPD excretion between each group before and after parturition. Both the plasma OC level and urinary DPD excretion of primiparous cows were significantly higher than those of multiparous cows in both the low and high dietary Ca groups.

show abstract

“…The calcium homeostasis of parturient cows depends on intestinal calcium absorption, and the bone resorption is suppressed or delayed for a week or more [27,28]. Physiological changes in plasma TRAP5b as well as bone markers such as HYP and BALP around parturition are necessary to examine in further studies, although there were several reports dealing with the spectrophotometric method for measuring plasma TRAP5b in cows [11,32,33].…”

Section: Discussionmentioning

confidence: 99%

“…Similarly, because skeletal disease (e.g., bone fracture, osteoarthritis, and osteomalacia) is often encountered in bovine practice, the assessment of bone markers may be helpful for determining diagnosis and prognosis. However, knowledge of bone markers is still limited to adult dairy cows during pregnancy and lactation [16,17,19,[31][32][33], cows with experimental hypocalcaemia [14], and cows fed a diet to prevent milk fever [7,11,18,24].…”

mentioning

confidence: 99%

See 1 more Smart Citation

Fluorometric Method for Measuring Plasma Tartrate-Resistant Acid Phosphatase Isoform 5b and Its Application in Cattle

Yamagishi

Kim

Miura

et al. 2009

The Journal of Veterinary Medical Science

View full text Add to dashboard Cite

ABSTRACT. This study determined the appropriate biochemical assay for measuring plasma tartrate-resistant acid phosphatase isoform 5b (TRAP5b) activity; this information is important to clarify the relationship between plasma TRAP5b and known biochemical bone markers in cattle. When plasma TRAP5b was measured using fluorometric and spectrophotometric methods, hemolysis products in plasma did not affect the former method. In plasma from healthy cattle, there was a good correlation (r=0.66) between the 2 methods. In agerelated profiles, plasma TRAP5b (r=-0.53), hydroxyproline (HYP, r=-0.56) and bone-specific alkaline phosphatase (BALP, r=-0.44) showed significant negative correlations with age; these three parameters decreased until 4 or 5 years of age and then remained constant. There were significant correlations between TRAP5b and HYP (r=0.83) or BALP (r=0.83). Our results show that the fluorometric assay can be performed with a high degree of precision and reproducibility without interference from hemolysis, and that the age-related changes in plasma TRAP5b, HYP, and BALP constitute additional background values for clinical guidance in bovine medicine.KEY WORDS: biochemical bone marker, cattle, fluorometry, plasma, tartrate-resistant acid phosphatase isoform 5b (TRAP5b).

show abstract

Association between Chages in Plasma Calcium Concentration and Plasma Tartrate-Resistant Acid Phosphatase Activity in Periparturient Cows.

Cited by 4 publications

References 25 publications

Plasma calcium concentrations are decreased at least 9 hours before parturition in multiparous Holstein-Friesian cattle in a herd fed an acidogenic diet during late gestation

Plasma calcium concentrations are decreased at least 9 hours before parturition in multiparous Holstein-Friesian cattle in a herd fed an acidogenic diet during late gestation

Effects of calcium intake and parity on plasma minerals and bone turnover around parturition

Fluorometric Method for Measuring Plasma Tartrate-Resistant Acid Phosphatase Isoform 5b and Its Application in Cattle

Contact Info

Product

Resources

About