Association between changes in body composition and the increasing prevalence of fatty liver in Japanese men

Imamura, Yasushi; Uto, Hirofumi; Oketani, Makoto; Hiramine, Yasunari; Hosoyamada, Kaori; Y, Sho; Hiwaki, Takuya; Baba, Yoshirou; Tahara, Kenji; Kubozono, Osamu; Kusano, Ken; Tsubouchi, Hirohito

doi:10.1111/j.1872-034x.2008.00383.x

Cited by 17 publications

(15 citation statements)

References 7 publications

(16 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Although our survey was not prospective in nature, these findings confirm that the major risk factors for FL are factors related to adiposity [1][2][3][4], not alcohol consumption, findings which agree with recent reports proposing a protective effect of alcohol intake [9][10][11][12][13]. We also confirmed that alcohol consumption tended to be negatively associated with FL in the limited number of subjects who had no history of ALT elevation, hypertension, dyslipidemia, or DM.…”

Section: Discussionsupporting

confidence: 92%

Alcohol drinking patterns and the risk of fatty liver in Japanese men

et al. 2010

Self Cite

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 92%

Alcohol drinking patterns and the risk of fatty liver in Japanese men

et al. 2010

Self Cite

View full text Add to dashboard Cite

show abstract

“…Previous studies have shown that PBF more accurately reflects body composition than BMI, although both BMI and PBF have been used for the evaluation of human health risks such as cardiovascular risk in clinical practice (12,13). A higher PBF and/or BMI often indicates a higher level of cardiovascular risk (14).…”

Section: Introductionmentioning

confidence: 99%

Percent body fat is a better predictor of cardiovascular risk factors than body mass index

Zeng

Dong

Sun

et al. 2012

Braz J Med Biol Res

174

117

View full text Add to dashboard Cite

The objective of the present study was to evaluate the predictive values of percent body fat (PBF) and body mass index (BMI) for cardiovascular risk factors, especially when PBF and BMI are conflicting. BMI was calculated by the standard formula and PBF was determined by bioelectrical impedance analysis. A total of 3859 ambulatory adult Han Chinese subjects (2173 males and 1686 females, age range: 18-85 years) without a history of cardiovascular diseases were recruited from February to September 2009. Based on BMI and PBF, they were classified into group 1 (normal BMI and PBF, N = 1961), group 2 (normal BMI, but abnormal PBF, N = 381), group 3 (abnormal BMI, but normal PBF, N = 681), and group 4 (abnormal BMI and PBF, N = 836). When age, gender, lifestyle, and family history of obesity were adjusted, PBF, but not BMI, was correlated with blood glucose and lipid levels. The odds ratio (OR) and 95% confidence interval (CI) for cardiovascular risk factors in groups 2 and 4 were 1.88 (1.45-2.45) and 2.06 (1.26-3.35) times those in group 1, respectively, but remained unchanged in group 3 (OR = 1.32, 95%CI = 0.92-1.89). Logistic regression models also demonstrated that PBF, rather than BMI, was independently associated with cardiovascular risk factors. In conclusion, PBF, and not BMI, is independently associated with cardiovascular risk factors, indicating that PBF is a better predictor.

show abstract

“…2,3) Many patients with nonalcoholic fatty liver disease (NAFLD) have a long and benign course; others, however, exhibit inflammation and fibrosis and progress to end-stage liver injury, such as cirrhosis, which is called as nonalcoholic steatohepatitis (NASH). NAFLD, including NASH, are now considered to be the hepatic manifestation of the metabolic syndrome.…”

Section: Discussionmentioning

confidence: 99%

“…Since the subjects in this study were healthy individuals employed at the same company and maintained a similar lifestyle, including their work and home life, during the 5-year study period, the present results were considered to be relatively reliable. The subjects in this study were limited to only men for the following reasons: first, the average prevalence of fatty liver classified according to sex was reported to be twice as high in men as it was in women in Japan; 2) second, estrogen levels might affect the development of fatty liver in women, since the prevalence of fatty liver increases rapidly in post-menopausal women. 5) In this study, those subjects, who were in therapy with chronic liver diseases, diabetes mellitus and/or hyperlipidemia, were excluded, because the medication to these diseases might influence to the occurrence of fatty liver disease.…”

Section: Discussionmentioning

confidence: 99%

“…In response to this prevalence of lifestyle-related diseases, the number of cases with fatty liver is also escalating. 2,3) Since liver dysfunction, most cases of which are thought to be caused by fatty liver, 4) is observed very frequently in combination with obesity in annual health check-ups, fatty liver is considered to be a component of, or at least a predictor of, metabolic syndrome. 5,6) Accumulating reports have shown the beneficial effects of coffee on liver function.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Coffee Consumption is Associated with a Lower Incidence of Fatty Liver in Middle-aged Men

Funatsu

Yamashita

Nakamura

2011

JOURNAL OF HEALTH SCIENCE

View full text Add to dashboard Cite

Whilst accumulating reports have shown the beneficial effects of coffee against chronic liver diseases, the effects of coffee against fatty liver have not yet been reported. In this cross-sectional and the followup studies, we investigated the effects of coffee on the production of fatty liver in healthy males, using ultrasonography. In the follow-up study, annual changes in daily coffee intake during the 5-year study period were compared between subjects who appeared to have fatty liver (fatty liver group) and those who did not appear to have fatty liver (non-fatty liver group) in the matched study according to age, body mass index (BMI) and daily exercise level. The effects of changes in daily coffee intake between both groups on the development of fatty liver were investigated after adjustments for related factors, such as BMI, daily coffee and alcohol intake and exercise level. In the cross-sectional study, the subjects with fatty liver were revealed to have a lower daily coffee intake than those without fatty liver. In the follow-up study, a significant difference in the changes in daily coffee intake was observed between the fatty liver and nonfatty liver groups with a decrease in daily coffee intake observed in the former group, compared with the change in the latter group. Further, daily coffee intake was negatively correlated with the development of fatty liver after adjustments for related factors. These findings suggest a protective effect of coffee against fatty liver.

show abstract

Association between changes in body composition and the increasing prevalence of fatty liver in Japanese men

Abstract: These results suggest that altered body composition, particularly increased BFP without an increase in BMI, has developed in men and is strongly associated with the increasing prevalence of fatty live amongst Japanese men.

Cited by 17 publications

References 7 publications

Alcohol drinking patterns and the risk of fatty liver in Japanese men

Alcohol drinking patterns and the risk of fatty liver in Japanese men

Percent body fat is a better predictor of cardiovascular risk factors than body mass index

Coffee Consumption is Associated with a Lower Incidence of Fatty Liver in Middle-aged Men

Contact Info

Product

Resources

About