association between CKD-associated pruritus and quality of life in patients undergoing hemodialysis presenting to nephrology division, Khyber teaching hospital Peshawar

Abstract

Background and Aim: Chronic kidney disease-associated pruritus (CKD-aP), commonly known as uremic pruritus is a frequent and inconvenient disease for patients undergoing hemodialysis. The purpose of the present investigation was to determine the association of CKD-associated pruritus with quality of life in patients undergoing hemodialysis presented to the nephrology division of Khyber Teaching Hospital Peshawar. Patients and Methods: This cross-sectional study was conducted on 227 CKD-associated pruritus patients investigated in the Nephrology Division of Khyber Teaching Hospital Peshawar from March 2022 to February 2023. Patients of either gender (>18 years) undergoing hemodialysis were enrolled. Demographic details, dialysis duration, duration of disease, and various comorbidities conditions were recorded based on a pre-designed questionnaire. Results: Out of 227 patients, there were 142 (62.6%) male and 85 (37.4%) female. The overall mean age was 40.82±6.82 years. The incidence of CKD-associated pruritus was 68.7% (n=156). The presence of various comorbidities such as diabetes mellitus, hypertension, hyperlipidemia, and cardiovascular disease was found in 30 (13.2%), 124 (54.6%), 16 (7.0%), and 6 (2.6%) respectively. The overall mean duration of CKD and duration on hemodialysis was 34.4 [12.0–48.0] months and 22.8 [12.0–36.0] months respectively.