Association between classic and specific bioimpedance vector analysis and sarcopenia in older adults: a cross-sectional study

Abstract

Background To verify (1) the association between classic and specific bioelectrical impedance vector analysis (BIVA) with body composition, hydration, and physical performance in older adults with and without sarcopenia; (2) which BIVA most accurately distinguishes sarcopenia. Methods A sample of 94 older adults with and without sarcopenia (29 men and 65 women, 60–85 years) was evaluated. The classic and specific BIVA procedures, Dual energy X-ray absorptiometry (DXA), and deuterium dilution were performed. Sarcopenia was defined by muscle weakness and low skeletal muscle index, while severity was indicated by low physical performance. Results The BIVA's potential to monitor hydration and muscle mass loss in older adults seems feasible. Classic and specific BIVA were able to distinguish sarcopenia in women (p < 0.001), but not in men. When the sarcopenia criteria were individually analyzed, both classic and specific BIVA were able to distinguish low skeletal muscle index in women, while only classic BIVA did for men. For the criterion of slow physical performance, only the classic BIVA showed severity differences for women. The vectors of adults without sarcopenia of both sexes tended to be positioned in the left region of the ellipses, revealing a predominance of soft tissues. Conclusions Classic BIVA has a distinct sarcopenic association with body composition, hydration, and physical performance in older adults, while specific BIVA was similar between groups. Both BIVAs are sensible to detect female morphological changes (skeletal muscle index) but not for functional (handgrip, 6-min walk test) sarcopenia criteria. These procedures are promising tools for monitoring sarcopenia risks during aging.

Identification and Characterization of Genomic Predictors of Sarcopenia and Sarcopenic Obesity Using UK Biobank Data

“…This is in line with the previous studies stating that low educational attainment [ 41 ], neuroticism [ 42 ], low testosterone levels [ 43 ], short stature [ 44 ], high alcohol [ 45 ], processed meat [ 46 ] and salt [ 47 ] intake, sedentary behavior (such as watching television) [ 48 ], smoking and physical inactivity [ 49 ] are associated with an increased risk of sarcopenia or low muscle strength, whereas coffee, magnesium, potassium, protein, vitamin D, water, oil fish, fruits and vegetables intake [ 46 , 50 , 51 , 52 , 53 , 54 ] have protective effects against sarcopenia.…”