Association between Clinical Signs of Oral Lichen Planus and Oral Health-Related Quality of Life: A Preliminary Study

Yiemstan, Sasirin; Krisdapong, Sudaduang; Piboonratanakit, Pornpan

doi:10.3390/dj8040113

Cited by 14 publications

(12 citation statements)

References 49 publications

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“…Although randomized clinical trial for OLP have been conducted, OH-QoL was measured as a secondary outcome [16,30]. Further, these studies mostly concentrated on evaluating the efficacy of drugs/medicines for symptomatic relief in patients; few authors evaluated the clinical improvement in signs or lesions [38].…”

Section: Discussionmentioning

confidence: 99%

Impact of Oral Lichen Planus on Oral Health-Related Quality of Life: A Systematic Review and Meta-Analysis

Yuwanati

Gondivkar

Sarode

et al. 2021

Clinics and Practice

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Oral health-related quality of life (OR-QoL) measurement in patients with oral lichen planus (OLP) can provide valuable information for the optimal management of their clinical conditions. The main objective of the present study was to assess the OR-QoL of patients with OLP as measured by the short-form Oral Health Impact profile-14 (OHIP-14) questionnaire. PubMed/MEDLINE, ISI/Web of Science, clinical trial registry, Embase, Scopus, and grey literature (via Google Scholar and Scilit) were searched. Reviewers independently screened titles/abstracts, assessed full-text articles, extracted data, and appraised their quality. Random effect analysis along with subgroup analysis for age, gender, and clinical type was performed. Seventeen studies were included. Mean overall OH-QoL was 15.20, [95% CI 12.176, 18.231]; a higher OHIP-14 score was seen in OLP patients, resulting in poor OH-QoL. The impact of OLP on OH-QoL life was moderate as compared to healthy subjects. However, medical treatment of the disease improved the OH-QoL and thus reduced the impact of OLP on it. OH-QoL among patients with OLP is generally poor. Clinicians and physicians should consider the OH-QoL of these patients as part of patients’ evaluation and modulate the administered treatment based on the OH-QoL response.

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Section: Discussionmentioning

confidence: 99%

Impact of Oral Lichen Planus on Oral Health-Related Quality of Life: A Systematic Review and Meta-Analysis

Yuwanati

Gondivkar

Sarode

et al. 2021

Clinics and Practice

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“…The following measurement tools can be utilised to evaluate the impact of OLP on patients' and Oral Health-Related Quality of Life (OHRQoL) in terms of physical, psychological and social dimensions [89]: Oral health impact profile-14 (OHIP-14) (short form) or 49 items (OHIP-49), consisting of only 8 items related to physical, psychological and social performance [90,91]; chronic oral mucosal disease quality of life index (COMDQ) [92,93]; oral impacts of daily performance (OIDP) [94].…”

Section: Oral Health-related Quality Of Lifementioning

confidence: 99%

Emerging potential of phototherapy in management of symptomatic oral lichen planus: A systematic review of randomised controlled clinical trials

Hanna

Dalvi²,

Tomov

et al. 2023

Journal of Biophotonics

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“…There was also an investigation of OHRQoL attributed to recurrent aphthous stomatitis in Thai children in a national oral health survey using OIDP [26]. Yiemstan et al [27] also used the Thai OIDP version for investigating the associations of OHRQoL and pain with clinical signs based on the Thongprasom sign scoring system in OLP patients.…”

Section: Introductionmentioning

confidence: 99%

Changes in the Oral-Health-Related Quality of Life of Thai patients with oral lichen planus after topical corticosteroid treatment: a 1-month longitudinal study

Kengtong

Piboonratanakit

Krisdapong³

2023

Preprint

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Background Oral lichen planus (OLP) is a common chronic inflammatory disease of the oral cavity that affects many patients’ daily living activities. The goal of treating OLP is to relieve symptomatic pain, and reduce inflammation. Topical corticosteroids are the first-line drug for treating OLP. OLP clinical trials should use a tripartite approach comprising clinical signs, symptoms, and quality of life. The Oral Impact on Daily Performances index (OIDP) is an Oral-Health-Related Quality of Life (OHRQoL) measure developed to assess the ultimate impacts. The aims of this study were to evaluate the clinical, pain and OHRQoL responses after treating OLP patients with topical corticosteroids for 1 month, and secondly to assess the relationships of changes in the clinical sign score, pain score, and OHRQoL. Methods Seventy-two OLP patients were recruited to assess their clinical outcomes and patient-based outcomes after treating them with topical corticosteroids for 1 month. The clinical outcomes were evaluated by the highest and total Thongprasom sign score. The patient-based outcomes were evaluated by a pain rating scale using a numeric rating scale (NRS), and OIDP. The self-rated overall changes in quality of life during the 1-month treatment period using the Patient Global Impression of Change (PGIC) were also recorded at the follow-up visit. Results This study comprised 59 women (81.9%) and 13 men (18.1%). The total OIDP percentage score was 19.1 ± 10.5 at baseline. The most commonly affected activities were Emotional stability (94.4%), followed by Eating (86.1%) and Cleaning the oral cavity (65.3%). At the 1-month follow-up visit, the highest Thongprasom sign score, total Thongprasom sign score, pain score and total OIDP percentage score were significantly reduced after treatment with topical corticosteroids (P < 0.01). None of the patients reported a lower quality of life. Forty-six percent reported the same or up to moderately improved, while 54% had a greatly improved quality of life as assessed by PGIC. There were no significant differences in the improvement of clinical and patient-based outcomes between these outcome groups. There were significant relationships between the difference in the highest Thongprasom sign score and the difference in total Thongprasom sign score (r = 0.293; P < 0.05), and the differences in total OIDP percentage score and the difference in pain score (r = 0.427; P < 0.001). The differences in the total Thongprasom sign score also significantly related to the difference in the total OIDP percentage score (r = 0.335; P < 0.01). However, no significant relationship was found between the difference in the highest Thongprasom sign score and the difference in patient-based outcomes. Conclusion Topical corticosteroids were significantly effective after 1-month treatment of OLP based on the clinical and patient-based outcomes. The OHRQoL improvement was significantly related to the reductions in pain and clinical severity. Trial registration The trial was registered at the Thai Clinical Trials Registry (TCTR identifier: TCTR 20221110001).

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Association between Clinical Signs of Oral Lichen Planus and Oral Health-Related Quality of Life: A Preliminary Study

Cited by 14 publications

References 49 publications

Impact of Oral Lichen Planus on Oral Health-Related Quality of Life: A Systematic Review and Meta-Analysis

Impact of Oral Lichen Planus on Oral Health-Related Quality of Life: A Systematic Review and Meta-Analysis

Emerging potential of phototherapy in management of symptomatic oral lichen planus: A systematic review of randomised controlled clinical trials

Changes in the Oral-Health-Related Quality of Life of Thai patients with oral lichen planus after topical corticosteroid treatment: a 1-month longitudinal study

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